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Biomedical subjects

U Patzschke

Publications and source records attributed to U Patzschke.

6 recordsLinked to original sources

[Left axis deviation and left anterior hemiblock in patients with essential hypertension during antihypertensive treatment (author's transl)].

The ECG's of 127 patients (81 men and 46 women) with uncomplicated essential hypertension were evaluated over a 4-year period of antihypertensive treatment. At the beginning of the study in 1973, 39 men (48%) showed ECG changes of left axis derivation (LAD) and 8 men (10%) a left anterior hemiblock (LAH), while 19 women (41) showed a LAD and 4 (9%) a LAH. During the course of the study no changes were noted in the 12 cases of LAH. However, two additional men developed signs of LAD in 1975/76 and one more in 1977/78. Men with LAH were somewhat older and women with LAH heavier in comparison to the total group. The combination of LAD and left ventricular hypertrophy (LVH) was evident in 9 men (11%) and 4 women (9%) at the beginning of the study, while 6 men (7%) and 1 woman showed a combination of LAH and LVH. Reversibility of LVH by ECG was observed in 10 patients (50%), but no concomitant changes in axis deviation were seen.

Antihypertensive Agents↗

[Regression of left ventricular hypertophy in the ECG during antihypertensive treatment: preliminary observations (author's transl)].

Typical signs of left ventricular hypertrophy (LVH) were present in the ECG of 36 (10 women, 26 men) of 127 persons with essential hypertension (46 women, 81 men). After a two-year course of combined drug treatment (chlortalidone, reserpine, methyl-dopa, hydralazine) with effective blood-pressure reduction LVH was still present in the ECG of 29, after a four-year course of only 15 among 36, i. e. a reduction in the presence of LVH of nearly 60%. Since the patients' body-weight remained unchanged during this period, the regression in ECG changes is ascribed to the effectiveness of the drug treatment.

Adult↗

Cardiovascular mortality in transient ischemic attacks.

Statistical analyses were made of the mortality of persons diagnosed as having definite TIA in an epidemiologic survey of a biracial Southern community. None of the usual risk factors associated with this illness such as heart disease, hypertension or diabetes appears to account for the excess deaths observed in a 10 year period of follow up.

Actuarial Analysis↗