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Biomedical subjects

U Sachs

Publications and source records attributed to U Sachs.

10 recordsLinked to original sources
PubMed1979

Intraocular pressure after aphakic penetrating keratoplasty "through-and-through" suturing.

Our clinical study was designed to determine whether "through-and-through" corneal sutures would prevent the postoperative intraocular pressure rise that occurs in 70% of aphakic eyes after uncomplicated penetrating keratoplasty. Twenty-five aphakic patients received the same operative procedure except that the corneal buttons of ten of them were sutured into place with "through-and-through" sutures. The intraocular pressures of patients with the "through-and-through" sutures were significantly lower than those of the other patients during the entire postoperative course.

Aphakia, Postcataract↗
PubMed1979

Pterygium and basic tear secretion.

In order to investigate the correlation between the occurrence of pterygium and dryness of the eyes, a Schirmer's No. 1 test was done on both eyes in 60 patients with unilateral pterygia. No difference was found between the mean basic secretion of tears in the diseased eyes (15.33 +/- 8.09 mm) and the fellow eyes (15.65 +/- 7.89 mm), and both were in the normal range for this test. This data suggest that dryness of the eyes cannot be regarded as the cause of pterygium.

Adult↗
PubMed1978

Corneal storage at room temperature.

Short-term eye banking is based mainly on moist chamber and McCarey-Kaufman medium (M-K medium) preservation. Both involve a controlled 4 C temperature for storage. Warming the cornea to room temperature, however, drastically affects the endothelial viability. On enzymatic staining and histological study, the M-K medium-stored rabbit corneas had more normal endothelium than did "moist chamber" eyes when storage was prolonged for seven days at room temperature. In human corneas that were kept at 4 C for 24 hours and then exposed to a temperature of 25 C, destruction of organelles had occurred by six hours and was increased by 12 hours. Corneas that were kept in M-K medium had relatively intact endothelium after four days, but cell disruption and vacuolation was present by the seventh day. The M-K medium, therefore, affords protection to tissue warmed to room temperature, where metabolic activity is resumed.

Adolescent↗
PubMed1977

[The uvea].

Explore the source record for details and available documents.

Uvea↗
PubMed1977

Use of the Bausch & Lomb Soflens Plano T contact lens as a bandage.

Twenty patients with corneal disease were treated with a recently released soft lens specifically designed for use as a bandage. Patients wore their lenses continuously 24 hr a day. The results were similar to those of previous studies conducted with other lens designs. Improvement was frequent (10 of 12 cases) for bullous keratopathy and corneal graft, burn, or neuroparalytic lesion; limited (1 of 4 cases) for dry-eye syndrome; and absent (4 cases) for irregular cornea and vernal keratoconjunctivitis. No difficulties were found with the concurrent use of medication.

Adolescent↗
PubMed1977

Fluorescein pupillary flow in aphakics with intact and spontaneous openings of the vitreous face.

The passage of fluorescein dye, injected into the general circulation, from the posterior to the anterior chamber was studied in 60 selected aphakic eyes between 2 days and 4 weeks after an uneventful cataract extraction. In a group of 22 eyes with intact anterior hyaloid, fluorescein was seen to pass only through the pupillary margin, mostly within 20 seconds of the beginning of the eye injection. In 24 eyes with rents in the anterior hyaloid the dye was seen percolating only through the vitreous face openings. No fluorescein passed through the pupillary margin or the peripheral iridectomy in this group of eyes. The appearance time of the dye was delayed to about twice the normal appearance time. In 8 eyes with rents in the anterior hyaloid the dye passed only through the pupillary margin. In 4 eyes with anterior vitreous rents the fluorescein appeared through the anterior vitreous face opening. From the analysis of the data it appears that the spontaneous breaks in the anterior vitreous face may represent a 'self-c,re' of pupillary and iridectomy block by the vitreous in aphakics in a high proportion of cases. It is our impression that 3 peripheral iridectomies and a very tight closure of the wound can prevent the complication of spontaneous breaks of the vitreous face.

Cataract Extraction↗
PubMed1976

Lymphocyte sensitivity to glucocorticoids.

We evaluated the possibility of identifying patients with open-angle glaucoma based on the in vitro behavior of their lymphocytes in the presence of glucocorticoids. Our results do not support the hypothesis that lymphocytes from patients with open-angle glaucoma, as compared to those from normal subjects, are more sensitive to the presence of corticosteroids in vitro. In addition, the degree of inhibition induced by glucocorticoids was closely related to the amount of activation of the lymphocyte membrane induced by different concentrations of phytohemagglutinin. Our results indicated that this may be a general phenomenon rather than one that is specific to a particular ophthalmological condition.

Dexamethasone↗
PubMed1975

Growth and transplantation of organ-cultured corneas.

Calf corneal buttons were grown in medium M199 supplemented with newborn calf serum (xenogeneic to the recipient) or rabbit serum (allongeneic to the recipient) and implanted interlamellarly into rabbit recipients. Implantation of buttons, grown in medium containing calf serum were rejected sooner than noncultured buttons. The rejection was quicker as the grafts were kept longer in culture. However, corneal buttons grown in medium containing rabbit serum showed, in general, a slower rejection process.

Animals↗
PubMedDate not supplied

Congenital hereditary corneal dystrophy associated with esotropia.

A family is described in which four of six siblings have congenital hereditary corneal dystrophy associated with esotropia. All cases had been erroneously diagnosed as and operated on for congenital glaucoma. The hereditary aspect of this association is discussed.

Child↗