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Biomedical subjects

U Saga

Publications and source records attributed to U Saga.

7 recordsLinked to original sources
PubMed1988

Demonstration of varicella-zoster virus antigens in the vitreous aspirates of patients with acute retinal necrosis syndrome.

Four cases of acute retinal necrosis (ARN) syndrome were studied virologically. Varicella-zoster virus (VZV) antigen was demonstrated by immunofluorescence in cells from vitreous aspirates of two cases. No herpes simplex virus (HSV) or cytomegalovirus (CMV) antigens were detected by the same technique. Antibody to VZV in vitreous fluid was present in two cases; however, it was not detected in sera. Although virus isolation was unsuccessful, these findings strongly suggest that VZV may play an important role in the etiology of ARN syndrome.

Adult↗
PubMed1984

Morphological study on glycosaminoglycans in the developing human vitreous.

The vascular and the avascular vitreous in 7th- and 8th-week human embryos and 9th-week fetuses were stained strongly by alcian blue, while marked decrease in staining by alcian blue was observed in 12th- and 13th-week human fetuses. The nature of alcian blue positive materials was identified as hyaluronic acid and chondroitin sulfate or dermatan sulfate by enzymatic digestion methods and the Scott-Dorling method. The results suggest that distinction between primary and secondary vitreous is difficult by classical histochemical techniques and electron microscopy, and that the vitreous glycosaminoglycans concentration seems to be high at 7th- and 8th-week embyonic stages and decreases at later fetal stages.

Chondroitin Sulfates↗
PubMed1983

Acute retinal necrosis (Kirisawa's uveitis).

Four cases of acute retinal necrosis accompanied by acute uveitis, retinal obliterative vasculitis and confluent yellow-white lesions in the peripheral fundus followed by retinal detachment are reported. The clinical course was rapidly progressive and the prognosis was poor despite various treatments. No systemic abnormality was found and etiology could not be identified. In reviewing the 40 cases so far reported, including our 4 cases, we came to the conclusion that acute retinal necrosis and Kirisawa's uveitis fall into the same clinical study.

Adolescent↗