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Biomedical subjects

U Schultz-Ehrenburg

Publications and source records attributed to U Schultz-Ehrenburg.

At least 19 recordsLinked to original sources
PubMed1995

Cutaneous microcirculation in skin lesions associated with chronic venous insufficiency.

BACKGROUND: There are various types of skin lesions in chronic venous insufficiency. OBJECTIVE: To determine an association between different skin lesions and different changes in the cutaneous vascular bed. METHODS: Twenty-eight patients with chronic venous insufficiency (CVI) without and with various types of skin lesions (ie, hyperpigmentation, lipodermatosclerosis, white atrophy, and venous ulcer) and 12 healthy control subjects were examined by video-capillaroscopy, transcutaneous oxygen tension measurement, photoplethysmography, and Doppler ultrasonography to detect disturbances of cutaneous microcirculation and venous macrocirculation. RESULTS: There were no significant differences between the different CVI groups with respect to their venous function disorder. However, important variations were noted in the cutaneous microcirculation. In all the patient groups, an increase in the mean halo diameter could be demonstrated even in clinically healthy skin. In all types of skin lesions, the mean capillary diameter was significantly enlarged. Severe morphological capillary changes and a significant reduction of the mean transcutaneous oxygen tension values were found in conjunction with lipodermatosclerosis and white atrophy and in the areas surrounding venous ulcers. CONCLUSION: The results of this study point to the conclusion that, once they have become established, microvascular disturbances play an independent role in the development of the skin lesions associated with CVI.

Adult↗
PubMed1995

Capillary microscopic findings in patients with CVI under different hydrostatic conditions.

Capillary microscopy in patients with CVI can show many morphological abnormalities like tortuous and elongated capillaries, heterogenous distribution of capillary tufts or microvascular thrombosis. Microcirculatory changes also become evident when examination is done under different hydrostatic conditions. For this purpose a new fiberoptic microscope was used, with an optical surface probe including a CCD camera. Fifteen patients with CVI stages I and II and 10 healthy volunteers were examined at the medial ankle area in supine, sitting and standing position. Patients with CVI showed larger vessel diameters in comparison to controls, the differences increasing with rising hydrostatic pressure. The perfusion type changed in both groups with venules becoming more evident especially in standing position.

Capillaries↗
PubMed1993

Stasis papillomatosis. Clinical features, etiopathogenesis and radiological findings.

Stasis papillomatosis can be divided into localized and widespread forms. Ten patients with this disease are discussed with emphasis on their clinical and lymphoradiological findings. Using isotope lymphography we were able to find an overall lymphostasis in only four patients. In all patients, local lymphatic disturbances were detected by means of indirect lymphography with intradermal lymph cysts as the most specific sign. Local dermal lymphostasis seems to be the common final pathogenesis in spite of different etiologies (ie, primary lymphedema, chronic venous insufficiency, trauma recurrent erysipelas, and local lymphangiodysplasia of unknown origin). A maximum variant was seen, following en-bloc resection of subcutaneous tissue in a patient suffering from congenital lymphedema.

Adult↗
PubMed1993

[A case of giant condyloma acuminatum. On differential diagnosis of giant condylomas from Buschke-Löwenstein tumors and verrucous carcinoma].

We report on a 67-year-old man with a large papillomatous tumour of the penis clinically resembling verrucous carcinoma. HPV 6 and HPV 11 DNA could be isolated by hybridization techniques. The tumour showed exclusively exophytic growth with anastomosing acanthosis and papillomatosis. Groups of vacuolated cells were present in the spinous and granular layers. Endophytic and destructive proliferations and cytologic criteria of malignancy were absent. This tumor was a giant condyloma acuminatum and not either a Buschke-Löwenstein tumour or a verrucous carcinoma. There was no recurrence 2 years after local excision. The differential diagnosis of giant condylomas and Buschke-Löwenstein tumours is discussed.

Aged↗
PubMed1992

[Perforating cutaneous amyloidosis].

Two patients, a 79-year-old man suffering from familial lichen amyloidosus and a 44-year-old women with biphasic cutaneous amyloidosis, developed small, centrally ulcerated papules. Histological and ultrastructural examination confirmed transepidermal elimination of amyloid. In contrast to other transepidermal elimination diseases, the material eliminated in perforating cutaneous amyloidosis is of epidermal origin.

Adult↗
PubMed1991

[D-SGP Duo--a new plethysmography for acral, arterial and venous blood pressure measurement].

This is to present a new portable plethysmograph using modern microprocessor technology, a two-channel digital strain gauge plethysmograph (D-SGP Duo). This system contains two strain gauges and a pressure gauge and has measuring programmes for thrombosis screening (venous occlusion test) and for the acral blood pressure measurement. For the first time it is possible to determine not only the acral systolic arterial pressure but also the acral venous blood pressure. Examples of application are given.

Blood Pressure↗
PubMed1991

[Tumor form of lymphostatic papillomatosis of the skin].

The case of a patient with two plantar papillomatous tumours that had had a relapsing course over 10 years is presented. The tumours were located on the right forefoot and the left great toe. Several operations were performed for different diagnoses, i.e. plantar verrucae, verrucous carcinoma and pyoderma vegetans. Histologically, the papillomas proved to be pseudocarcinomatous hyperplasias with multiple ectatic dermal lymph plexuses. Indirect lymphography revealed a circumscribed lymphatic dysplasia with cystic-ectatic cutaneous vessels within the tumour area. Draining lymphatic collectors were conspicuously reduced in number. Isotope lymphography showed a normal lymph transport rate from the foot to the groin. It is concluded that the circumscribed disturbance of lymphatic drainage is the decisive cause of the reactive papillomatous hyperplasia. Thus, these papillomas clinically resembling verrucous carcinoma represent the tumour variant of a papillomatosis cutis lymphostatica.

Foot Diseases↗
PubMed1989

[Pagetoid reticulosis of the Ketron-Goodman type].

The case of a 79-year-old woman with widespread pagetoid reticulosis (Ketron-Goodman type) is presented. The nature of the epidermal cellular infiltrate in pagetoid reticulosis of the Ketron-Goodman type was examined by immunohistochemical methods and by electron microscopy. On ultrastructural examination the infiltrating cells proved to be medium-sized and large Sézary-type and blastoid cells. Immunohistochemically, the epidermal infiltrate was composed of approximately 80% immature T cells (OKT 16) and 30% proliferating cells (Ki 67). Mature T cells (CD 5) were found to account for only 15-30% of all cells in the infiltrate. These results suggest that pagetoid reticulosis (Ketron-Goodman type) is a malignant T-cell lymphoma, which is characterized, in addition to the epidermotropic behavior common to all T-cell lymphomas, by innidiation and in-situ spread within the epidermis.

Aged↗
PubMed1989

[Isotype lymphography findings in sclerotherapy, varicose exeresis and excision of autologous venous transplants for arterial reconstructions].

In an isotope lymphography study on 24 patients (38 legs), the influence of complete sclerosation therapy of trunk varicosis of the great and small saphenous veins according to Tournay is examined before and, on average, four weeks after treatment. The isotope lymphography parameter was defined as the ratio of the outflow from the foot to the influx to the groin area (quotient Q). The results showed no significant change in Q after treatment compared with the starting values. Thus, sclerosation therapy did not result in any impairment of lymphatic transport. In contrast, of the 9 patients (12 legs) treated by varicose exeresis who were referred for isotope lymphography there were 8 cases (i.e. 9 legs) of impaired lymphatic transport. However, this was a pre-selected patient group. Three further patients were examined by isotope lymphography after resection of a saphenous segment for arterial reconstruction. These revealed excessive lymphatic transport disturbances which were quantified for the first time. Vascular surgeons should include this complication in their explanatory talks with patients.

Adult↗
PubMed1988

[Plaque-formed cutaneous mucinosis with telangiectasis].

We report the case of a 71-year-old man with a combination of circumscribed euthyroid myxodermia and clinically visible telangiectasias. We excluded the possibility of a sympathetic lesion being the cause of the telangiectasias by using a new method, transcutaneous PO2 measurement. Different possible reasons for the simultaneous occurrence of mucinosis and telangiectasias are discussed.

Aged↗