[Biopsy procedures in sarcoidosis].
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Biomedical subjects
Publications and source records attributed to U Seelig.
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Bronchospasmolytic tests with Terbutaline (Arubendol-Aerosol) were performed in 23 pts without or with an additional nebulizer. The use of a nebulizer in pts with a perfect handling of inhalers seems to be not better than the inhalation without nebulizer. The most reliable parameter of bronchospasmolytic effects is the airway resistance (Rt).
The study demonstrates the results of 203 patients with COLD in a follow-up of 4-6 years. The investigations include the clinical state, lung function tests, blood gas analyses and measurements of pulmonary arterial pressure (PAP). One hundred and six of these 203 patients were investigated 3 times within 4-6 years. Clinical state, oxygen partial pressure and airways' resistance showed the best correlation with the PAP at rest and under exercise. In 54 patients (= 51%) the pulmonary arterial pressure increased up to a pulmonary hypertension. In 37 patients (= 35%) it decreased, out of them in 13 to normal values. Only in 15 patients (= 14%) the PAP did not change. We conclude, that a single measurement of the pulmonary arterial pressure can only be a marker of the general prognosis in COLD, but not of the individual prognosis. So we need further follow-up studies for the correct assessment of the individual prognosis dependent on the clinical state in each case.
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