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Biomedical subjects

U Solzbach

Publications and source records attributed to U Solzbach.

8 recordsLinked to original sources

[ACPA reaction in atypical Wegener's disease. Diagnostic test].

Clinical and biopsy findings in six patients (aged 29-64 years), suspected of having Wegener's granulomatosis, were not diagnostic. Cardinal signs were skin necroses, isolated deficits of cranial nerves, sudden amaurosis, renal failure with shunt sepsis and lung opacities suspicious of tumour. Only positive tests for anti-cytoplasmatic antibodies (ACPA) in serum made the diagnosis and led to appropriate treatment. This simple yet highly specific immunofluorescence test should be performed in every case of vasculitis of uncertain cause, even if typical clinical signs of Wegener's granulomatosis are at first absent.

Adult

[Status of the technic of angiography procedures].

Angiocardiography continues to expand inspite of competitive non-invasive imaging techniques (echocardiography, CT, nuclear magnetic resonance). Only angiography yields images of sufficient spatial and temporal resolution as they are needed for coronary diagnostic work and interventional catheter therapy. Angiographic systems are mono- or biplane with high degree of mobility and flexibility for oblique and angulated projections. Currently available systems do not fulfill the requirements. Image resolution and contrast are today satisfactory, however, still not sufficient for interventional techniques. Only digital image processing will allow further improvement, thereby enhancing contrast and detail while reducing radiation dose (pulsed, high-contrast fluoroscopy, on-line image processing). Cine-filming seems not needed in all cases. In the future, angiocardiography will hardly be needed for study of cardiac chambers, valves or great vessels. Instead, specialized systems of extreme mobility and flexibility with high resolution and digital image processing for image improvement and documentation, radiation reduction for coronary and general arterial diagnostic and therapeutic interventions will be developed.

Angiocardiography

Derivation of spatial information from biplane multidirectional coronary angiograms.

UNLABELLED: Modern biplane multidirectional isocentric X-ray equipment delivers the image information necessary for spatial computations from two simultaneous 2-dimensional coronary angiographic pictures. Using the tools of analytical geometry, the spatial position of well definable points in the fields of view of the two image-intensifiers can be calculated from their corresponding projections knowing the geometrical properties of the system stands. The method developed is independent of the angle between the projections and is applicable even if hemiaxial views are used. The mathematical formulas necessary for these spatial computations are derived. By means of calculating the radiological magnification factor, the method was validated using a wire with known diameter as reference object. 360-diameter measurements of the wire filmed in 18 different simultaneous biplane projections resulted in a mean error of 3.14%. In addition, catheter measurements of routine coronary angiograms yielded a mean diameter of 2.64 +/- 0.19 mm (mean +/- SD, real diameter 2.66 mm). CONCLUSION: Using this algorithm, a reliable determination of spatial coordinates of distinct points of interest is possible as prerequisite for absolute quantitative measurements from biplane angiograms.

Angiocardiography