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Biomedical subjects

U Sprandel

Publications and source records attributed to U Sprandel.

29 records · Page 2Linked to original sources
PubMed1977

[Cystic degeneration of the vessel walls. The differential diagnosis of obliterative angiopathies: (author's transl)].

Cystic degeneration of the vessel wall is a rare disease predominantly localized in the region of the popliteal artery. It appears in the frequent clinical picture of intermittent claudication. Two cases are presented. The etiology of this syndrome is not clear. The appearance of intermittent claudication, preferably in middle-aged men without risk factors is typical for an obliterative angiopathy. Angiophically there are smooth-walled stenoses or occlusions, especially of the popliteal artery, with an otherwise inconspicuous vascular system. The prognosis after surgical treatment by excision or resection is good.

Adult↗
PubMed1976

Metabolism of maltose in perfused rat liver and in isolated hepatocytes.

The conversion of 14C-maltose into glucose, lactate and 14 CO2 was studied in perfused livers from fed and fasted rats and in isolated hepatocytes. Maximal glucose production was 30 mM x g-1 x h-1; half-maximal rates were found with 3 mM maltose. About 0.01 % of the radioactivity infused was recovered as 14CO2. The addition of maltose had no effect on rates of oxygen consumption, lactate production or ketogenesis. The data suggest that maltose did not serve as a major substrate for biosynthetic or energy producing processes under the conditions of the perfused rat liver.

Animals↗
PubMed1975

[Streptozotocin diabetes in a miniature pig (author's transl)].

The intravenous application of 60 mg streptozotocin/kg body weight to a Hanford miniature pig 8 days after a first dose of 30 mg/kg led to a diabetes with loss of insulin response to glucose, hyperglycaemia, glucosuria and a considerable increase of triglycerides and cholesterol. The application of 40 mg streptozotocin/kg to a second pig had no effect.

Animals↗
PubMed1975

Utilization of intravenous maltose.

Ten healthy male subjects received an infusion of 10% maltose solution at a rate of 0.5 g/kg body weight/h for 345 min. Blood maltose levels rose continuously for the first hours; after 285 min a constant level was maintained. Concomitantly increasing maltosuria occurred; the total renal maltose excretion averaged 30.4% of the administered dose. In addition to maltose losses, considerable glucosuria (up to 16% of total carbohydrate excretion) was found. The glucosuria occurred in spite of normal blood glucose levels. Serum insulin did rise during maltose infusion.

Adult↗