PubMed Health⌕ Search

Biomedical subjects

U Wied

Publications and source records attributed to U Wied.

17 recordsLinked to original sources
PubMed1987

Pleurodesis in spontaneous pneumothorax by means of tetracycline. Follow-up evaluation of a method.

The validity of previous recommendation of early thoracoscopy and tetracycline pleurodesis in the management of spontaneous pneumothorax without thoracoscopically visualized true cyst was assessed under non-trial, normal hospital conditions. Among 46 patients treated during a year, seven underwent immediate thoracotomy following finding of large cysts. Of the remaining 39 patients, 11 had recurrence of pneumothorax after a median of 11 (range 2-64) weeks. Repeat thoracoscopy then showed large cyst or bullous emphysema in seven cases. Tetracycline pleurodesis was again performed in the others. In continued observation for at least 2 years there were no further recurrences. The importance of meticulous thoracoscopy is stressed. The demonstrated diagnostic errors do not detract from the value of tetracycline pleurodesis when spontaneous pneumothorax is caused by rupture of only tiny blebs on the surface of an otherwise healthy lung. The procedure is fast, simple and efficacious.

Adolescent↗
PubMed1985

Postoperative survival of patients with potentially curable cancer of the colon.

The association between histopathologic findings and postoperative survival in 442 patients with potentially curable carcinomas of the colon has been analyzed using Cox's regression model. The prognostic variables included in the study were age, sex, stage of disease according to Dukes' classification and Broders' grading, as well as presence/absence at the time of operation of venous and nerve invasion. The overall five-year postoperative survival rate was 46.6 percent. Using a model including all prognostic factors, sex and Dukes' classification were not found to be associated with survival. Broders' grading and/or nerve invasion yielded only a borderline statistical significance in the model that included all factors. The invasion of veins was almost always associated with invasion of nerves.

Adult↗
PubMed1983

Tetracycline versus silver nitrate pleurodesis in spontaneous pneumothorax.

Silver nitrate pleurodesis as prevention against recurrence in primary spontaneous pneumothorax was started in our department on an empiric basis. In a controlled trial in 1981 the method was found to be as good as earlier stated, but the method has a high number of side effects and has never been widely accepted. In a prospective, controlled trial comparing silver nitrate pleurodesis with tetracycline pleurodesis, we found no differences in recurrence frequency, but the time of hospitalization was significantly longer in the silver nitrate group (p less than 0.05). Furthermore, we found a decrease of exudation and a decreased use of analgetics in the tetracycline group. As a consequence of the investigation, we have abandoned the silver nitrate method and now recommend tetracycline pleurodesis as the treatment of choice in primary spontaneous pneumothorax in patients with only tiny blebs on the surface of the lung.

Adolescent↗
PubMed1982

Ultrasonography, 99mTc-DIDA cholescintigraphy, and infusion tomography in the diagnosis of acute cholecystitis.

Ultrasonography, 99mTc-DIDA cholescintigraphy, and infusion tomography of the gallbladder were compared in a prospective study comprising 45 consecutive patients clinically suspected of having acute cholecystitis. The diagnosis of acute cholecystitis was established or excluded by operation in 35 patients, by oral cholecystography in 5, and by intravenous cholangiography in 5. The predictive values of a positive and a negative test were 100% and 83%, respectively, by ultrasonography and 98% and 88% by cholescintigraphy. Corresponding values for infusion tomography were 87% and 33%. The results suggest that in patients suspected of having acute cholecystitis, 99mTc-DIDA cholescintigraphy and ultrasonography provide a rapid and reliable diagnosis.

Acute Disease↗
PubMed1981

Silver nitrate pleurodesis in spontaneous pneumothorax.

Pleurodesis provoked by instillation of silver nitrate as prevention against recurrence in primary spontaneous pneumothorax has been used for many years in the Department of Thoracic Surgery, Gentofte Hospital, University of Copenhagen. The treatment was originally instituted on a theoretical empiric basis. In a prospective, controlled investigation of pleurodesis versus simple drainage the empiric observations have been confirmed. With simple drainage we found ipsilateral recurrence of pneumothorax in 45%, while no recurrences in the pleurodesis group were found during an observation period of 5-19 months. The difference was statistically significant. The therapeutical gain using pleurodesis was 45% +/- 30%. Silver nitrate pleurodesis results in a longer hospitalization, raises the number of pleurocentesis because of increased pleural effusion and results in more pain than simple drainage. It is, however, our experience that the considerable therapeutical gain more than compensates for these negative effects. We recommend pleurodesis as the treatment of choice in primary spontaneous pneumothorax in patients with only tiny blebs on the surface of the lungs.

Adolescent↗
PubMed1981

Randomised trial comparing Proximate stapler with conventional skin closure.

The Proximate stapler was compared with usual skin closure in a randomized trial, with 137 patients having elective abdominal and breast surgery. The median duration of skin closure with the Proximate stapler was 80 seconds, which was significantly shorter than the median of 242 seconds with conventional closure. No difference was found with regard to wound infection, but pain was more frequent after stapling.

Clinical Trials as Topic↗