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U Wolfram

Publications and source records attributed to U Wolfram.

4 recordsLinked to original sources
PubMed1992

Electroencephalography and evoked potentials: a PC-based analysis program for laboratory courses in physiology.

A computer program (EEG Analysis) was developed for the preclinical laboratory course in physiology held for medical and dental students. It offers an off-line analysis of a set of typical and frequently occurring physiological and pathological electroencephalogram (EEG) and evoked potential (EP) recordings, which are stored in an IBM-compatible personal computer (PC) system. The users are requested to measure and analyze the data sets and to work through a base of questions relevant in the frame of the particular topic. The program is structured in several exercises: calibration, pickup of non-EEG signals (eye movements, chewing), waveforms in EEG recordings from awake subjects (alpha-waves, beta-waves), desynchronization of cerebral activity (visual activation, acoustic activation, mental activation), habituation of cerebral activity upon acoustic stimuli, EEG recordings from asleep subjects (different sleep stages, sleep-specific EEG signals), epileptic seizures, and EPs (principle of averaging, visually evoked potentials in different cortical areas). The program runs under MS-DOS and is network capable. The software structure ensures maximal flexibility for rapid changes and adaptations of the program to specific needs of a particular EEG course. The program has been used for three years, and the response from > 800 students has been consistently positive.

Acoustic Stimulation↗
PubMed1988

The contractile response of vascular smooth muscle to thrombin and its inhibition by thrombin inhibitors.

Thrombin (0.1-30 NIH-U/ml) caused a contractile response of rabbit aortic rings. The vasocontraction was independent upon intact endothelium, however in deendothelialized vessels the contractile effect was more pronounced. The thrombin-induced vasocontraction was diminished in calcium-free medium; the same effect was attained by the calcium channel blocker verapamil at high concentrations. In human femoral and saphenous vein strips thrombin produced a contractile effect, too, which was very low and inconsistent in femoral arterial strips. To inhibit the contractile response of vascular smooth muscle to thrombin, higher concentrations of both the specific tight-binding inhibitors hirudin and beta Nas-Gly-(pAM)Phe-Pip were required than for the inhibition of fibrinogen clotting.

Animals↗
PubMedDate not supplied

[Medium-term results using the cement-free link endoprosthesis. Ribbed shaft V socket].

Since 3/84 340 primary implantations with the uncemented "Link" hip system (Rib-Type V socket) were done. The results with an average follow up of 3.2 years are published. Only 2.17% revision had to be suffered in the rib stem, while 0.77% socket revision had to be done. According to the score of Merle d'Aubigné the values of pain increased from 2.87% to 5.38%, walking ability from 3.68% to 5.27% and the range of motion from 133 degrees to 199 degrees. A high rate of good and satisfying results proved this anatomical implant system to be a good alternative in total hip replacement in younger patients.

Adolescent↗