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Biomedical subjects

Ulf Tiede

Publications and source records attributed to Ulf Tiede.

4 recordsLinked to original sources

Three-dimensional atlas of lymph node topography based on the visible human data set.

Comprehensive atlases of lymph node topography are necessary tools to provide a detailed description of the lymphatic distribution in relation to other organs and structures. Despite the recent developments of atlases and guidelines focusing on definitions of lymphatic regions, a comprehensive and detailed description of the three-dimensional (3D) nodal distribution is lacking. This article describes a new 3D atlas of lymph node topography based on the digital images of the Visible Human Male Anatomical (VHMA) data set. About 1,200 lymph nodes were localized in the data set and their distribution was compared with data from current cross-sectional lymphatic atlases. The identified nodes were delineated and then labeled with different colors that corresponded to their anatomical locations. A series of 2D illustrations, showing discrete locations, description, and distribution of major lymph nodes, was compiled to form a cross-sectional atlas. The resultant contours of all localized nodes in the VHMA data set were superimposed to develop a volumetric model. A 3D reconstruction was generated for the lymph nodes and surrounding structures. The volumetric lymph node topography was also integrated into the existing VOXEL-MAN digital atlas to obtain an interactive and photo-realistic visualization of the lymph nodes showing their proximity to blood vessels and surrounding organs. The lymph node topography forms part of our whole body atlas database, which includes organs, definitions, and parameters that are related to radiation therapy. The lymph node topography atlas could be utilized for visualization and exploration of the 3D lymphatic distribution to assist in defining the target volume for treatment based on the lymphatic spread surrounding the primary tumor.

Anatomy, Cross-Sectional↗

Computer-based anatomy a prerequisite for computer-assisted radiology and surgery.

RATIONALE AND OBJECTIVES: The aim of the study is to show the possibilities opened up by three-dimensional (3D) computer-based models of the human body for education in anatomy, training of radiological and endoscopic examinations, and simulation of surgical procedures. MATERIALS AND METHODS: Based on 3D data sets obtained from the Visible Human and/or clinical cases, virtual body models are created that provide an integrated spatial and symbolic description of the anatomy by using interactive color/intensity-based segmentation, ray casting visualization with subvoxel resolution, a semantic network for knowledge modeling, and augmented QuickTime VR (Apple Computer, Inc, Cupertino, CA) movies for presentation. RESULTS: From these models, various radiological, endoscopic, or haptic manifestations of the body can be derived. This is shown with examples from anatomy teaching, correlation of x-ray images with 3D anatomy for education in radiology, gastrointestinal endoscopy, correlation of ultrasound images with 3D anatomy in endoscopic ultrasonography, and simulation of drilling in temporal bone surgery. CONCLUSION: The presented models provide a means for realistic training in interpretation of radiological and endoscopic images of the human body. Furthermore, certain surgical procedures may be simulated realistically. Used as a complement to the current curriculum, these models have the potential to greatly decrease education times and costs.

Anatomy↗

Volume cutting for virtual petrous bone surgery.

A profound knowledge of anatomy and surgical landmarks of the temporal bone is a basic necessity for any otologic surgeon. Because this knowledge, so far, has been mostly taught by limited temporal bone drilling courses, our objective was to create a system for virtual petrous bone surgery that allows the realistic simulation of specific laterobasal surgical approaches. A major requirement was the development of an interactive drill-like tool, together with a new technique for realistic visualization of simulated cut surfaces. The system is based on a volumetric, high-resolution model of the temporal bone, derived from CT. Interactive volume cutting methods using a new multivolume scheme have been developed. In this scheme, cut regions are modeled independently in additional data volumes using voxelization techniques. The voxelization is adapted to successive cutting operations as needed for the simulation of a drill-like tool. A new visualization technique was developed for artifact-free rendering of sharp edges, as formed by the intersection of a cut and an object surface. The new multivolume visualization technique allows high-quality visualization of interactively generated cut surfaces. This is a necessity for a realistic simulation of petrous bone surgery. Our system therefore facilitates comprehension of the complex morphology, and enables the recognition of surgical landmarks, which is most important if injury to delicate organs (e.g., the facial nerve or auditory ossicles) is to be avoided. The system for virtual petrous bone surgery allows the simulation of specific surgical approaches with high-quality visualization. The user can learn about the complex three-dimensional anatomy of the temporal bone from the viewpoint of a real otosurgical procedure.

Anatomy, Cross-Sectional↗

Virtual endoscopy using spherical QuickTime-VR panorama views.

Virtual endoscopy needs some precomputation of the data (segmentation, path finding) before the diagnostic process can take place. We propose a method that precomputes multinode spherical panorama movies using Quick-Time VR. This technique allows almost the same navigation and visualization capabilities as a real endoscopic procedure, a significant reduction of interaction input is achieved and the movie represents a document of the procedure.

Colonography, Computed Tomographic↗