Biomedical subjects

Urmi Shah

Publications and source records attributed to Urmi Shah.

3 recordsLinked to original sources

PubMed2006

Probable edge defect in Acrysof single-piece intraocular lens.

The purpose of this article is to report an edge defect in single-piece hydrophobic acrylic intraocular lens (IOL) observed during a routine phacoemulsification procedure. The chip was successfully removed intraoperatively with a McPherson's forceps. However, six months postoperatively patient complained of a disturbing glare due to posterior capsular folds originating from the site of IOL defect. Patient was advised, however refused to undergo Nd:Yag laser capsulotomy to relieve the symptoms. This case highlights the necessity to check each foldable IOL under the microscope before loading it into the cartridge, for possible edge defects.

Female↗

PubMed2005

Outcome of corneal transplant rejection: a 10-year study.

PURPOSE: To study the incidence of graft rejection and the predictive factors for its reversibility. METHODS: It is a retrospective study of 1927 consecutive penetrating keratoplasties performed between January 1990 and January 2000 with more than 6 months follow up. A total of 224 rejection episodes were noted in 183 patients. Of these, 184 first rejection episodes were included in this study. RESULTS: The incidence of first rejection episode was 9.55%. Of patients 87% were symptomatic during the episode with vision loss being the commonest. The average time of onset of rejection was 15.25 +/- 14.4 months (median 11.7 months). In total, 53.3% of rejections occurred within 1 year after surgery. Of the patients who completed minimum 3 months follow up after the rejection episode, the rate of reversibility was 63.3%. Major predictive factors for a poor outcome after rejection were repeated grafting and associated anterior vitrectomy during surgery. The reversibility of the episode did not differ significantly with the modality of treatment used, but treatment with intravenous steroids within 7 days of onset of rejection may have a role in reducing the recurrences of rejection episodes, thus increasing the graft survival. CONCLUSION: Regrafts and associated anterior vitrectomy were significant risk factors for a poor outcome following rejection episode.

Adolescent↗

PubMed2002

Performance of a truncated-edged silicone foldable intraocular lens in Indian eyes.

PURPOSE: To study the role of truncated-edged silicone foldable intraocular lenses (IOLs) in preventing posterior capsule opacification (PCO) in Indian eyes. SETTING: Cornea and Anterior Segment Service, L.V. Prasad Eye Institute, Hyderabad, India. METHODS: This prospective study evaluated 39 Indian patients (39 eyes) with a mean age of 55.4 years who had uneventful implantation of the CeeOn Edge 911A IOL (Pharmacia). All IOLs were placed in the bag. Except in 4 patients, the capsulorhexis margin overlapped 360 degrees on the IOL optic periphery. The mean follow-up was 10.9 months (range 6.5 to 13.0 months); 32 patients were followed for 1 year. RESULTS: Intraoperatively, posterior capsule fibrosis was noted in 7 patients. Diffuse haze was noted in the IOL optic in 1 patient. Clinically significant PCO did not occur in any case. One patient had clinically nonsignificant (grade 1) PCO at the 6- and 12-month follow-up visits. Although epithelial pearl accumulation (Soemmering's ring) was seen beyond the edge of the IOL in the 32 patients followed for 1 year, the epithelial pearls were central only in the patient with grade 1 PCO. Significant cell deposits were noted in 1 patient who had fibrinous uveitis at the 1-week postoperative visit; both resolved by 1 month. All eyes achieved a best corrected visual acuity of 20/30 or better. CONCLUSIONS: The CeeOn Edge 911A IOL was well tolerated in Indian eyes, and the posterior capsule remained clear. Larger patient groups with a longer follow-up will provide more useful information.

Adult↗