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Biomedical subjects

V A Babaev

Publications and source records attributed to V A Babaev.

10 recordsLinked to original sources

[Effect of trimecaine on myocardial contractility and the rhythmoinotropic properties of the myocardium in hypoxia].

In the papillary muscles from 14 adult rats and myocardial specimens from 14 newborn ones, trimecaine in doses of 1.10(-6) and 5.10(-6) g/ml produced a dose-dependent negative inotropic effect, reversed the rhythmoinotropic correlation into a negative one and minimized the efficiency of postextrasystolic potentiation. Trimecaine in the former dose reduced hypoxic damage of myocardial specimens in the both groups as reflected by a smaller amplitude of hypoxic contracture and better contractility recovery following a hour hypoxia. It is suggested that reduction in hypoxic contracture and damage to the myocardium occur in the presence of trimecaine from limited Ca2+ entry into myocytes via the Na-Ca turnover mechanism.

Acetanilides↗

[Optimization of anesthesiological management of the delivery in women with moderate and high myopia].

Eye fundus, functional state of retina, intraocular pressure, central hemodynamics and cerebral circulation were examined in 290 patients with moderate or severe myopia and in 25 healthy women during pregnancy, in parturition period and after labors. 255 labors were conducted by way of natural maternal passages under prolonged epidural anesthesia at the first and second stages of labor. Epidural anesthesia was accompanied by decreasing vasoconstriction and both cerebral and ocular circulation improvement. There was no any progress in myopia in a year after delivery. The labor by way of normal maternal passages were proved to be carried out under epidural anesthesia in patient with moderate and severe myopia.

Anesthesia, Epidural↗

[Anesthesia in preterm labor].

The authors analyze early neonatal morbidity in 87 preterm babies and the values of perinatal mortality of newborns born to mothers whose labor was anesthesized by different methods. The task of this study was to assess the effect of long epidural anesthesia (LEA) used for preterm labor pain relief on the survival of small-for-date babies. Standard anesthesia of labor is compared to LEA. LEA ensured adequate analgesia and stable hemodynamics; moreover, it protected the intrauterine fetus from hypoxic injuries to the central nervous system due to normalization of uterine contractility and uteroplacental bloodflow and relaxation of the muscles of the fundus of the uterus.

Adult↗