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Biomedical subjects

V A Borisov

Publications and source records attributed to V A Borisov.

At least 19 recordsLinked to original sources
PubMed1989

[Microcirculatory function in various clinical forms of HB and HD viral infections].

Bulbar microphotographic vasography was used in 100 patients with different clinical patterns of HBV and HDV infections to study microcirculation over time. The data obtained were correlated to the data of the immunoassays. The relationship between microcirculatory disorders recordable during HBV and HDV infections and immunopathological responses and conditions occurring in those infections is under discussion.

Acute Disease↗
PubMed1988

[Relation of the immunosuppressivity of virulent Shigella to the structure of O antigen].

The capacity of filtrates of virulent Shigella cultures (VSC) and their different fractions to render avirulent strains, injected intraperitoneally into mice simultaneously with these filtrates, capable of suppressing immune response (delayed hypersensitivity) has been studied. Among the fractions of VSC filtrates, the lipoid fraction soluble in the mixture of ethanol and ether has proved to be active. Active factors can be extracted from VSC filtrates by means of immunosorbents obtained from antibodies of pertinent specificity. VSC filtrates are completely inactivated by treatment with phenol and trichloroacetic acid. These data suggest that the immunosuppressive factors of shigellae, responsible for their capacity to suppress immunological memory, are incorporated into the O-antigen of these bacteria.

Animals↗
PubMed1988

[Microcirculatory function in viral hepatitis A and B].

Microcirculation was studied over time in 51 patients with acute viral hepatitides types A and B using bulbar microphotographic vasography. The results were compared with some immunological indices (the blood level of circulating immune complexes, the platelet aggregation test). The expression of microcirculatory changes correlated both with a type of virus hepatitis and the severity of disease. The relationship of disorders in the system of microcirculation with immune factors, in particular with immunopathological reactions developing during HBV infections, was discussed.

Adolescent↗
PubMed1987

[Shigella toxicity in immunological tolerance].

The toxic effect of killed and live Shigella sonnei cultures on normal mice and on mice, tolerant to Shigella O-antigen and to human erythrocytes of different blood groups (in the ABO system) was under study. The toxicity of shigellae, introduced intraperitoneally, has been found to depend on their viability, on their capacity for penetration into the blood, and on the split character of immunological tolerance to Shigella antigens.

ABO Blood-Group System↗
PubMedDate not supplied

[The effect of the antigen-induced splenic suppressor factor on the immune response to different antigens].

Quick-frozen spleen of mice immunized with sheep red blood cells was homogenized and centrifuged. Supernatant was used as a source of suppressor factor (SF). It was shown that SF inhibited antibody immune response to thymus-dependent antigens and delayed hypersensitivity reaction. SF did not inhibit antibody formation to thymus-independent antigen. SF activity disappeared after its treatment with anti-Ig immunosorbent.

Animals↗