[Importance of screening tests for hepatitis B antigen and transaminase in blood service institutions for the prevention of viral hepatitis].
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Biomedical subjects
Publications and source records attributed to V A Burlev.
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Tropism of the antigen of hepatitis B to the antibodies against normal serum proteins was revealed by the method of affine chromatography; this pointed to the possibility of the presence in the HBs-antigen structure of some antigenic determinants of the serum proteins or to the association of serum proteins with the HBs-antigen. A change of the isoelectric spectrum of the HBs-antigen and its tropism in affine chromatography to the antibodies against serum proteins possibly depended both on the nonhomogeneity of the antigenic determinants included into the composition of the antigen, and on the presence of the HBs-antigen--HBs-antibody or HBs-antigen--serum proteins complexes.
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The effect of picasol (a preparation of n-3 polyunsaturated fatty acids) on the serum lipid spectrum was studied upon administration of the drug to 60 pregnant women with a high-risk of developing placental insufficiency during II-III trimesters of pregnancy in accordance with a program of randomized placebo controlled double blind trial. In the absence of differences in the level of lipid spectrum parameters prior to picasol administration we found in the III trimester a reliably low content of triglycerides and cholesterol of extremely low density lipoproteids in patients who received picasol.
Correctness of a real-time graphic image was checked by a multi-system integral nomogram showing changes in the condition of certain homeostasis parameters with regard for a condition of systemic oxygen transport. Concentrations of TB-active products and of medium-weight molecules were examined at the moment of finding the integral dot of oxygen transport to different quadrants of the nomogram obtained on the basis of blood samples taken from 286 obstetric and gynecological patients. Correctness and timeliness of real-time nomograms' images as well as occurrence of hypo- and hyperoxic conditions as a response to changing parameters of systemic oxygen transport were proven.