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Biomedical subjects

V A Fulginiti

Publications and source records attributed to V A Fulginiti.

13 recordsLinked to original sources
PubMed1979

Amebic liver abscess in children: clinical and epidemiologic features.

Amebiasis, that is, infection with Entameba histolytica, continues to be endemic in the United States, with liver abscess occurring as an infrequent but constant complication. Seven cases are reported, with epidemiologic investigation of two. Reliable findings in hepatic abscess include fever, abdominal pain, respiratory distress, tender abdomen, and large, tender liver. Anemia, elevated white count with left shift, and the radiographic findings of an elevated right hemidiaphragm are constant. Epidemiologically, amebiasis occurs in clusters in the United States with person-to-person transmission predominant in spread. Infection is associated with poor sanitation and crowding. Investigation of the families of two patients documented 9/21 carriers and an additional 3/21 who were seropositive, as well as crowding and poor sanitation. In this country, treatment of a patient with amebic disease should include investigation of his home and family.

Adolescent↗
PubMed1977

Parallel tubular arrays in severe combined immunodeficiency disease: an ultrastructural study of peripheral blood lymphocytes.

The ultrastructure of the lymphocytes from three children with severe combined immunodeficiency disease (SCID) is described. Parallel tubular arrays (PTA) were found in a large percentage of circulating lymphocytes (53%, 41%, and 13%) in three SCID patients when compared to age-matched controls. The size of these inclusions was quite variable, with some attaining a length of 1.7 micrometer. They contained a tubular substructure with a diameter of 36--44 nm. The PTA were mostly located in the centriolar and Golgi regions of the cytoplasm, and were sometimes membrane bound. A centriolar origin of the inclusion was suggested. A second inclusion, the tubuloreticular structure, was found in only 1.4% of the circulating lymphocytes from one SCID patient. The origin of the PTA and its occurrence in severe combined immunodeficiency disease are discussed.

Female↗
PubMed1976

Controversies in current immunization policy and practices: one physician's viewpoint.

Immunization offers the best available method preventing diseases which exact huge tolls in terms of comfort, life and economic stability of humans. However, immunization is a mixed blessing because of unavoidable risks to recipients of almost any biologic product. Only by careful attention to the balance of risks between an immunization procedure and its corresponding disease will we achieve a rational, sound and appropriate policy and practice. This report details the author's analysis and opinion concerning some current controversies in immunization policy and practice. The reader is cautioned that the report represents one viewpoint; others report differing or even contradictory interpretations of the data presented, leading to different or even opposing views. The purpose of this report will be ably served if the reader considers the data himself (herself) and reaches an independent, informed opinion.

Adolescent↗
PubMed1976

Immunization practice: some important guidelines.

The right of patients (parents) to know, in detail, the risks inherent in immunization procedures is an important issue. There is legal precedent for holding a physician or drug manufacturer liable for hazards inherent in immunizing materials even if no negligence is involved.

Child↗
PubMed1976

Pseudomonas cepacia pneumonia in a child with chronic granulomatous disease and selective IgA deficiency.

A 6 1/2 year-old boy with chronic granulomatous disease (CGD) and selective IgA deficiency developed a chronic progressive pneumonia which failed to respond to several conventional combinations of antimicrobial therapy. On lung biopsy, Pseudomonas cepacia was obtained in pure culture, sensitive to chloramphenicol, tetracycline, kanamycin and nalidixic acid. With specific therapy, he slowly recovered. P. cepacia has not been previously described as a cause of persistent pneumonia in immunodeficient children. The occurrence of CGD and selective IgA deficiency together is a very rare combination of immunodeficiencies.

Child↗