[Transposition of great vessels with a defect in the interventricular wall and high pulmonary hypertension. Hemodynamics and results of correction].
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Biomedical subjects
Publications and source records attributed to V A Garibian.
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The article analyses experience in surgical treatment of critical stenosis and atresia of the pulmonary artery with an intact interventricular septum in 53 infants. The patients were divided into two groups: group A--26 patients with a hypoplastic cavity of the right ventricle (RV), and group B--27 patients with a normal RV cavity. In group A, 15 patients underwent transpulmonary valvulotomy in combination with subclavian-pulmonary anastomosis by means of a Gortex prosthesis, 6 were subjected to isolated transpulmonary valvulotomy, and 5 patients underwent reconstruction of the RV outlet tract under conditions of extracorporeal circulation. In group B, 3 patients were treated by transpulmonary valvulotomy and subclavian-pulmonary anastomosis with a Gortex prosthesis, 16 by isolated valvulotomy, and 8 patients by reconstruction of the RV outlet tract under extracorporeal circulation. Six (22.2%) patients in group B died; 18 (69.2%) patients in group A died. Experience shows that in patients with critical stenosis of the pulmonary artery without RV hypoplasia preference is given to transpulmonary valvulotomy with occlusion of the venae cavae or, in marked infundibular stenosis of the RV--to reconstructive operation on the RV outlet tract under conditions of extracorporeal circulation. Transpulmonary valvulotomy in combination with subclavian-pulmonary anastomosis is advisable in patients with atresia or critical stenosis of the pulmonary artery and RV hypoplasia.
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Two-dimensional and Doppler echocardiographic findings were compared with those of coronary angiography and cardiac catheterization in 31 patients (11 with pulmonary atresia and 20 with critical pulmonary stenosis in the presence of ventricular septum). Two-dimensional echocardiography was found to accurately define the linear dimensions, volumes, and ejection fraction of the ventricles in patients with the disease. Continuous Doppler echocardiography is a valuable tool for measuring right ventricular systolic pressure and pressure gradient between the right ventricle and the pulmonary artery. Two-dimensional and Doppler echocardiographies enable surgical tactics to be chosen in most cases without interventions.
The article generalizes the experience in surgical treatment of Fallot's tetrad in 20 infants. Radical correction of the anomaly was carried out under extracorporeal circulation and deep hypothermia with reduced volume rate of perfusion. Plastics of the conus arteriosus alone was performed in 6 patients, transanulus and the pulmonary trunk in 4 patients. Two patients died, the hospital lethality was 10%. A clinical effect was produced in all the other patients. The relation of systolic pressure in the left ventricle to that in the right ventricle was 0.56 +/- 0.1, the systolic pressure gradient between the right ventricle and the pulmonary artery was 18 +/- 4.2 mm Hg. Various degree of regurgitation at the pulmonary valve was revealed after the operation in all patients. It was maximum (34 +/- 10%) in transanulus plastics.
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The results of intracardiac examination of 37 patients with anomalous origin of the left coronary artery from the pulmonary trunk were studied. On the basis of anatomo-angiographic++ comparisons the authors point out the characteristic features of coronary circulation and affection of the left ventricular myocardium which determine the clinical manifestations of its dysfunction. The functional condition of the left ventricle was appraised depending on the character of development of the intercoronary collaterals.
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Contemporary requirements to angiocardiographic examination in congenital heart diseases are discussed. It is shown that patients with high pulmonary hypertension should be examined by means of left ventriculography and aortography which permit the diagnosis of intraventricular septal defect combined with patent ductus arteriosus, common arterial trunk and open atrioventricular canal. Auxiliary methods of examination in such a commonly encountered anomaly as Fallot's tetralogy and atresia of the pulmonary artery are described, which make it possible to judge the condition of the pulmonary artery. The necessity is demonstrated for performing a two- and multiserial examination in complete and corrected transposition of the major vessels, dual origin of the aorta and pulmonary artery from the right ventricle, and in cases with a solitary ventricle. The role of angiocardiography in appraising the volume of cardiac cavities in patients with congenital heart diseases is noted.
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