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Biomedical subjects

V A Golubkov

Publications and source records attributed to V A Golubkov.

15 recordsLinked to original sources
PubMed1993

[Invasive interventions with computerized tomography guidance].

Invasive interventions (diagnostic and therapeutic) were conducted on 125 patients. Fifty-six has diseases of the lungs, 16 of the mediastinum, 4 of the pleura, 17 of the liver, 2 of the pancreas, one of the spleen, 15 of the kidneys, 7 of the retroperineal space, two of the soft tissues, and 5 patients had diseases of the skeletal bones. Biopsy was combined with aspiration of the renal cyst content in 7 cases. The diagnostic value of biopsy under control of CT was 86% (106 cases); negative and pseudonegative results were recorded in 18 (14%) patients. The efficacy of biopsy is determined by such factors as the size of the lesion and the depth of its localization in the involved organ, the character of the pathological process and the region of its localization, the site from which the material is collected, and the needles used. Among 7 patients with therapeutic interventions, 5 had good and 2 had satisfactory immediate results. Complications were revealed in 4 (3.3%) patients, pneumothorax was encountered most frequently.

Adult↗
PubMed1992

[The potentials of computed tomography in the treatment of cysts and inflammatory diseases of the internal organs].

Computed tomography (CT) is used more and more often recently in the treatment of some surgical diseases of the internal organs. The subject of discussion in this work are the results of treatment of cysts and pyoinflammatory diseases of the internal organs. The work was conducted on CT IV generation "QUAD 1" of the CMS firm (England). Needles measuring 14-18d in diameter (Charrière scale) were used for aspiration. A total of 23 therapeutic interventions were performed in 19 patients with exudative pleurisy (1 patient), pleuritis (4), pulmonary abscesses (1), abscesses of the liver (1), abscesses of the subhepatic and subdiaphragmatic spaces (2), cysts of the liver (1) and kidneys (1 patient). Among the interventions 21 were aspirations and 2 drainage of the abscess. A mechanical syringe is used lately for more effective evacuation of the contents. The removed contents, ranging in volume from 10.0 to 600.0 ml, was subjected to cytological, biochemical, and bacteriological analysis. A single puncture is sufficient, as a rule, for aspiration of the cyst contents, one-stage aspiration from cysts of both kidneys may be conducted (as was the case in two of our patients). 96% alcohol was used as the sclerosing agent. In cases of small abscesses aspiration may be repeated for removal of the contents, irrigation of the cavity, and administration of antibiotics. In abscesses measuring more than 10 cm drainage is advisable. Control CT examination is conducted once a week. The condition of the cavity is appraised by combining CT with its contrast study. The immediate results were good and satisfactory in 17 (94.7%) patients.(ABSTRACT TRUNCATED AT 250 WORDS)

Abscess↗
PubMed1990

[Present-day diagnosis of pulmonary thromboembolism].

Main complains, clinical appearance of the disease and laboratory findings have been evaluated for 28 patients with pulmonary embolism and its complications. The diagnosis made at x-ray and computed tomography examination proved valid in 85% of cases confirming the efficiency of their combined use in this disease. The author believe a comprehensive approach promising in solving the problem of pulmonary embolism.

Acute Disease↗
PubMed1975

[The relationship between several biological properties of tumors and their metabolism].

Cytochemically, in smears-impressions of gastric and pulmonary tissue the authors studied alpha-glycerophosphate (a GPDH), succinate (SDH) and dihydroorthate (DDG) dehydrogenases that gives one an idea on the activity of energetic processes and initial stages of nucleic acid synthesis. It seems that a quantitative cytochemical analysis of the enzymic profile of tumor will allow some suggestions as to a capacity of tumors to metastasize and a degree of resistance to the therapy employed.

Antineoplastic Agents↗