[Subatrophic status of mucous tunic of pharynx in servicemen and principles of its treatment].
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Biomedical subjects
Publications and source records attributed to V A Gorbunov.
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The efficacy of parallel and successive chemoradial treatment of patients with nasopharynx carcinoma was investigated in the radiological center of Burdenko MMCH. The main group consisted of 42 patients, the control group included 44 patients. They were from 21 to 78 years old. 71% of the patients had the 3rd and the 4th stages of the tumor process; 29% had the 1st and the 2nd stages; 68,6% had the metastatic nodal involvement of regional zones. The radial therapy of the locoregional zone was administered by means of the splitting course using the classic method of fractionating a dose up to the total optimal dose of 64-70 Gr. Polychemotherapy consisted of 6 courses cisplatin, farmarubicin, and platinum. Due to the treatment the 5-year survival rate increased from 41,2% to 78,5% (P < 0,001). With the metastatic nodal involvement of regional zones that rate reduced from 83,3% to 72,8% (P > 0,05) in the main group and from 63,8% to 31,9% (P < 0,001) in the control group.
We have developed a simple and physically clear picture of adiabatic rapid passage (ARP) in molecules in solution by careful examination of all the conditions needed for ARP. The relaxation effects were considered in the framework of the Landau-Zener model for random crossing of levels. The model enables us to include into consideration non-Markovian Gaussian-correlated noise. It explains all the numerical results obtained in the first paper of the series [B. D. Fainberg and V. A. Gorbunov, J. Chem. Phys. 117, 7222 (2002)], in particular, that for positive chirp pulse excitation relaxation favors more efficient population transfer with respect to the relaxation-free system with frozen nuclear motion. We also relate parameters of non-Markovian Gaussian-correlated noise with irreversible dephasing time of an optical transition by calculating the photon echo signal attenuation.
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