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Biomedical subjects

V A Isabaeva

Publications and source records attributed to V A Isabaeva.

5 recordsLinked to original sources
PubMed1989

[Mast cell and blood coagulation functions during prolonged noradrenaline administration].

During the long term noradrenaline injection (0.56 microgram/kg/min-2 hours during six days) the number of connective tissue mast cells decreases in dogs. Mature cells disappears and the percentage of young forms increases. Marked degranulation develops. 5-10 cell groups and chains are formed. The increase of free heparin level and the activation of anticoagulant unit hemostasis correspond to these changes. It is due to mast cells discharge of biologically active heparin which is an unspecific adaptogen.

Animals↗
PubMed1976

[Circadian rhythms in connective tissue].

A study of circadian rhythms in the connective tissue showed cell elements (particularly histiocytes) to be characterized by circadian rhythms of the metabolic processes. This is expressed in a distinct diurnal activity of the succinic dehydrogenase (SDH) and lactic dehydrogenase (LDH). In the processes of adaptation to the high altitude hypoxia the activity of SDH and LDH was higher than in control, but dynamics of the changes of their activity repeated the changes in control group. It is concluded that circadian rhythms of the metabolic processes in the connective tissue were sufficiently stable: no visible changes were observed during adaptation to high altitudes.

Adaptation, Physiological↗
PubMedDate not supplied

[Decrease in the radiation effect in the lymphoid organs of animals adapting to altitude].

Adaptation to altitude hypoxia exerts a positive effect on the cell density of lymph organs of gamma-irradiated animals. It also reduces radiation degradation of DNA, its availability to DNase in the nuclear chromatin and disorders in the activity of DNA polymerases. The role of inhibition of radiation-induced degradation of chromatin DNA in the protective effect of altitude adaptation on the cell density of lymph organs is discussed.

Adaptation, Physiological↗