[Xanthogranulomatous cholecystitis].
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Biomedical subjects
Publications and source records attributed to V A Iudin.
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Experimental investigations and experience with treatment of 74 patients with pancreonecrosis have shown the highest effectiveness of associated usage of hemosorption and external elimination of lymph from the thoracic duct. Associated detoxication for pancreonecrosis facilitates to rapidly decrease the level of the intoxication which is demonstrated by positive dynamics of biochemical and toxicological parameters of blood and lymph.
Experiments were conducted to study the acid-base equilibrium of blood in pancreatitis and in combination with laser irradiation of venous blood by the intravascular method through a light guide. Irradiation of blood was attended by inhibition of metabolic acidosis development, which was evidently linked with improved blood oxygen transport function in response to exposure to the laser beam.
Inpatient examinations included 17 patients with necrosis of the pancreas (4 patients had hemorrhagic and 14 fat necrosis): synthetic lymphocyte activity was studied by the luminescent method and the erythrocyte content of adenyl nucleotides by thin-layer chromatography in the toxic phase of pancreatitis. Synthetic lymphocyte activity was found to be decreased and the ATP pool of erythrocytes exhausted in the toxic phase of pancreatitis. Intravascular laser irradiation of the blood caused recovery of lymphocyte activity and increase in the ATP content in erythrocytes.
Data are given on the specific features of the diagnosis and treatment of more than 2000 pancreatitis patients. In 388 of them the clinical signs of affection of the spine were verified by X-ray: intervertebral osteochondrosis and osteoarthrosis of the costovertebral articulations. The appropriate correction of changes in the spine promotes more rapid improvement of the state of the pancreas.
Experimental (118 experiments) and clinical (30 patients) investigations have shown a positive effect of endovascular irradiation of blood with the helium-neon and ultraviolet lasers on recovery of homeostasis in pancreatitis and peritonitis. The procedure stimulates the erythrocyte bioenergetics, reduces the degree of haemic hypoxia and increases nonspecific immunological reactivity.
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Basic systemic hemodynamic parameters were compared during intravenous anesthesia with calypsol (ketamine) and diazepam, promedol and diazepam, fentanyl and diazepam, fentanyl and sombrevin in 120 patients operated on the lungs with conventional and high-frequency jet ventilation. The studies have shown that in conventional controlled lung ventilation there were no distinctions in hemodynamic parameters depending on the type of the anesthesia. In high-frequency jet ventilation, specific hemodynamic effects of calypsol were observed. Unlike other anesthetics, calypsol administration is associated with elevated central venous pressure, increased cardiac output and enhanced left ventricular work, which can be accounted for by higher venous return.
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