Biomedical subjects

V A Kosarev

Publications and source records attributed to V A Kosarev.

At least 19 recordsLinked to original sources

PubMed1995

[Acute pancreatitis in children].

The article shows the results of treatment of 66 children, aged from 5 months to 14 years, with acute pancreatitis (AP), 17 of them had the destructive form of the disease. The causes of AP development in children are analysed and the criteria of its diagnosis are determined. Particular attention is focused on the methods of the diagnosis of destructive forms, ultrasonic examination of the abdominal cavity and laparoscopy among others. Sparing surgical policy for pancreonecrosis was applied, including injections of protease inhibitors and antibiotics around the pancreas, drainage of the omental bursa and abdominal cavity, and cholecystostomy. A scheme of postoperative management of these patients is suggested. Discrete plasmapheresis was applied in severe intoxication. Two patients with destructive AP died due to the development of severe hepatorenal failure.

Acute Disease↗

PubMed1994

[Treatment of generalized forms of suppurative peritonitis in children].

The article deals with the experience in the treatment of 220 children with generalized forms of purulent peritonitis of various origin (appendicular, posttraumatic, consequence of destructive pancreatitis and other inflammatory processes in the abdominal cavity). A scheme of therapeutic measures which were applied for the control of infection and endotoxicosis is given. They include homeostasis by means of extracorporeal detoxification, differentiated immunocorrection, quantum therapy, and other modern methods of treatment. Mortality among the patients was 5.9%, while before the introduction of the described methods into practice it was 13.2%.

Child↗

PubMed1993

[Treatment of generalized purulent appendicular peritonitis in children].

Experience in the treatment of 137 children with a most severe and complicated course of generalized purulent peritonitis of appendicular genesis is generalized. It is shown that such patients must be concentrated in centers of pediatric surgery providing the possibility of applying a complex of diagnostic examinations and therapeutic measures, including purposeful antibiotic therapy, differentiated immunocorrection, and effective detoxification. The detoxification and immunocorrection effect of discrete plasmapheresis with two-stage "washing out" of the red cells is illustrated in the discussion of 22 cases. It is pointed out that in operations for generalized purulent peritonitis the abdominal cavity must not only be cleansed but also drained adequately and intubation of the intestine must be carried out with aspiration of its content for 3-5 days and application of enterosorption through an intestinal tube. A complex of organizational and therapeutic measures made it possible to reduce considerably the mortality rate in acute appendicitis and its complications in the Moscow Region.

Acute Disease↗

PubMed1991