[Analysis of chromatin conformational flexibility in drosophila embryo cell free system].
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Biomedical subjects
Publications and source records attributed to V A Kraevskiĭ.
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Influence of specific nucleotide sequences on the constitutive transcriptional activity of the Rous sarcoma long terminal repeats (LTR) was studied. The possible function of different elements of the transcriptional control region of the avian retroviral LTR was discussed on the basis of a comparative analysis of the effect of specific nucleotide insertions on LTR activity in vivo and in vitro.
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The effect of hyperacetylation of histones on the packing of nucleosomal fibers into higher-order structures was studied. The organization of the higher-order levels of packing of hyperacetylated and normal chromatin in intact hepatocytes of green marmoset (CV1 line) was compared by using the intercalating agent chloroquine diphosphate to change the axial twinting of DNA of internucleosomal linkers.