[State of the prostaglandin and cyclic nucleotide system in microwave resonance therapy of peptic ulcer].
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Biomedical subjects
Publications and source records attributed to V A Kutsenok.
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Based on an investigation of indices of enzymatic spectrum of the blood, cyclic nucleotides, ultrasonic and rheographic examination of the liver the authors confirmed high efficiency of using electromagnetic radiation in the millimeter-wave range in ulcer disease and concomitant diseases of the liver.
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Effects of MMW electromagnetic radiation on the immunity status were studied in 92 patients with ulcer of duodenum before and after the course of treatment which consisted of 8-10 sessions of exposure, using acupuncture points for the purpose, for 20-25 minutes daily, the immunocorrective action of the method employed having been made evident. Both quantitative and qualitative indices for the immunity system return to normal, with the ratio of lymphocyte regulatory subpopulation being restored, functional activity previously suppressed, of immunocompetent cells being enhanced, the level of autoimmune processes lowered.
An effect was studied of electromagnetic radiation of the millimetric wave band (EHF EMR) on ultrastructural processes of the mucosa and healing of ulcer in 10 patients with duodenal ulcer. Biopsy specimens were taken from the base of the margin of the ulcer and in the area 1 cm from the margin of the ulcer defect before the treatment, after 5 and 10 sessions of EHF EMR to acupuncture points. EHF EMR was found to exert a stimulating effect on the processes of ulcer regeneration. Seen after session 5 are layers of proliferating poorly differentiated enterocytes, activation of immune and autoimmune processes, normalization of the hemomicrovessel endothelial cell structure, filling in the ulcer defect with a newly formed granulation tissue in which, among fibroblasts, macrophages, mast cells and lymphocytes, there prevail plasmic cells with an augmented secretion of immunoglobulins, increase in proliferation of epitheliocytes, with their differentiation slowing down, and a complete epithelialization of the ulcer following ten treatment procedures.