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Biomedical subjects

V A Landar'

Publications and source records attributed to V A Landar'.

5 recordsLinked to original sources
PubMed1990

[The determination of erythrocyte deformability using a filtration method].

Red cell deformability was assessed in donors, patients with chronic renal insufficiency, and with thermal injuries by filtration through special filters. Filtration of donor red cells decreased their count but insignificantly; in patients with chronic renal insufficiency this characteristic was lowered, particularly so before hemoperfusion, whereas after hemoperfusion red cell deformability improved. Changes of red cell deformability in patients with thermal injuries is an objective criterion reflecting the status of the erythron peripheral component in connection with the severity of injury and course of its healing.

Burns↗
PubMed1989

[A device for determining erythrocyte deformability].

A device for determining red cell deformability is described. The studies have demonstrated that in normal subjects the red cell deformability is sufficiently high and the cells penetrate through a filter with pore diameter of 5 microns, whereas in the patients with chronic renal insufficiency this parameter is reduced (p less than 0.001).

Equipment and Supplies↗
PubMed1989

[Surface architectonics and erythrocyte deformability in patients with terminal stage of chronic kidney failure].

Red cell deformability was examined in donors and patients with chronic renal insufficiency; the red cell surface architectonics before and after filtration was under study. The red cell ability to deformation was found reduced in the patients, the level of nontransitional prehemolytic forms of red cells increased, and the count of discoid cells reduced. These data permit assessing the red cell ability to deformation.

Erythrocyte Deformability↗
PubMedDate not supplied

[Anemia in patients with chronic kidney failure undergoing systematic hemodialysis treatment].

A study of 24 patients with chronic renal failure and varying degrees of uremia and clinical symptoms was carried out in order to assess the mechanisms of anemia developing in patients on systematic hemodialysis for chronic renal failure. Blood clinical and biochemical parameters were evaluated. Sternal bone marrow puncture was performed to assess erythron status. Proliferative activity of bone marrow erythroid cells was assessed by autoradiography. Ineffective erythropoiesis was studied using MacManus' PAS test. The results of the study suggest that proliferative activity of bone-marrow erythroid cells is reduced while ineffective erythropoiesis is increased in patients with terminal chronic renal failure, treated by systematic hemodialysis, and largely explain the mechanism of anemia in these patients.

Adolescent↗