[Acute disorders of mesenteric circulation].
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Biomedical subjects
Publications and source records attributed to V A Mikhaĭlichenko.
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Results of the treatment of 48 patients with surgical sepsis are analyzed. In 24 of the patients hemosorption with charcoal SKN-2M was used, in 18 patients the intravenous injection of dioxidine was included in the complex treatment. The use of hemosorption and dioxidine made the treatment 5,7 days shorter and reduced lethality.
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The incidence of cancer of the pancreatoduodenal organs (the pancreas, major duodenal papilla, extrahepatic bile ducts, duodenum) is reported according to the autopsy findings obtained at two clinical hospitals (provincial and municipal) of Donetsk city during the period from 1957 to 1973. There is a tendency to the increased mortality due to cancer of the localization concerned against the background of the reduced total mortality.
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Observations over 250 patients with cancer of the pancreas allowed the author to present the data on metastasization and proliferation of cancer in the adjacent organs. Proliferation on the pancreatic head cancer was observed in 55.4% of patients and most frequently in upper mesenterial vessels, the portal vein, hepatic and splenic artery. In cancer located in distal portions of the gland proliferation was noted in 60% of observations, and mainly in the hepatoduodenal ligament and mesentery of the small and large intestine. Metastasization was more frequently noted both in tumor located in distal portions of the gland and in generalization of the process. Thus, cancer of distal portions of the pancreas shows a more aggressive course than cancer of the pancreatic head.
In 76 patients with cancer of the organs of the pancreatoduodenal zone the functional state of the liver and its morphocytochemical structure were studied during the operation and postoperatively. A considerable impairment of functional tests of the liver, its enzymic activity, mineral metabolism and the microelements content was revealed. Simultaneously with functional-enzymic disturbances in the liver also morphocytochemical changes were found to be pronounced.
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