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Biomedical subjects

V A Raĭskiĭ

Publications and source records attributed to V A Raĭskiĭ.

At least 19 recordsLinked to original sources

[Clinico-pathogenetic patterns in the development of febrile attacks in schizophrenia].

Patients with febrile attacks of schizophrenia showed clinical and laboratory correlations between the severity of the clinical picture on the one hand and parameters of the leukocyte index of intoxication, ESR, the NaK ratio and 17-CS secretion, on the other. The authors consider the possible causes of elevated levels of dopamine in the urine and of beta-lipoproteins and creatine phosphokinase in the cerebrospinal fluid. The study has revealed anti-brain antibodies and sensitization of leukocytes to neuroleptics. A possible role of neural viral infection in the etiology and pathogenesis of the studies conditions is discussed.

Adrenal Cortex↗

[Clinical picture and course of the neuroleptic malignant syndrome (acute febrile neuroleptic encephalopathy)].

On the basis of their observations and management of 23 cases of the neuroleptic malignant syndrome (MNS) the authors draw a conclusion that this syndrome is similar to extrapyramidal-psychotic side effects of neuroleptic therapy. Different variants of the course of this complication of neuroleptic therapy attended by hyperthermia are considered. The authors propose the term 'acute febrile neuroleptic therapy' which incorporates all hyperthermic variants of the course of this complication of neuroleptic therapy, varying from mild transitory one to the MNS. Criteria of the early diagnosis are presented.

Adult↗

[Role of somatic factors in the clinical picture and therapy of so-called masked depressions].

In somatic and psychiatric examination of 38 patients with masked depression under variable somatic masks the authors have revealed clear-cut symptoms of depressions and a high rate of somatic pathology. They believe that peripheral somatic disorders determine to a certain degree both nature and projection of the somatic mask. The questions of masked depressions are discussed.

Adult↗

[Therapeutic approaches to the treatment of febrile schizophrenia].

Analysis of the literature data on the use of various therapeutic approaches to the treatment of febrile schizophrenia has shown that so far psychiatry does not possess such methods of treatment which could allow the complete prevention of lethal outcomes in this disease. The article describes a new original approach to the treatment of patients with febrile schizophrenia, aimed at the correction of homeostatic disturbances with the complete refusal from neuroleptics in the febrile period of an attack. This therapeutic approach proved highly effective in 24 out of 26 patients and enabled preventing lethal outcomes in all cases. Study of the characteristics of febrile schizophrenia based on the authors' own observations and case reports made it possible to identify three variants of the time-course of the febrile attack. The article also considers the specificities of therapy with respect to the identified variants of the time-course of febrile attacks.

Adolescent↗

[Comparative findings concerning the effect of elenium and seduxen on the cardiovascular system].

The authors studied the effect of seduxen and elenium on 169 patients, particularly their pulse frequency, arterial pressure, electro- and polycardiogramms in a single administration of the drugs parenterally and in a long-term per os administration. A parenteral introduction of both drugs was accompanied by a slight bradycardial effect. However, high doses of seduxen (0.34--0.5 mg/kg) lead to states of tachycardia. Unlike elenium which did not exert a hypotensive effect, seduxen displayed a mild and in some cases significant hypotensive action.

Adolescent↗