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Biomedical subjects

V A Rykov

Publications and source records attributed to V A Rykov.

15 recordsLinked to original sources
PubMed1990

[Distribution of alpha 2-macroglobulin and pregnancy-associated protein A and alpha 2-glycoprotein in human placenta].

By means of immunoperoxidase technique staining localization in the mature placenta of a number of highly molecular proteins--alpha 2-macroglobulin and associated with pregnancy alpha 2-glycoprotein and protein-A--has been determined. These proteins are predominantly determined in syncytiotrophoblast and decidual cells. Similarity in distribution of the proteins in question is determined not only by identity of their receptors, but is evidently caused by community of their functional properties.

Decidua↗
PubMed1990

[Antitumor effectiveness and nephrotoxicity of oxoplatinum].

Studies on such transplantable murine tumors as MOPC-21 plasmacytoma and Krebs-2 carcinoma showed oxoplatinum course administration to produce necrosis in solid tumors and pronounced alterations in surviving tumor cells. Single applications of 15 or 20 mg/kg were followed by an increase in the mean survival of Krebs-2 ascites carcinoma--bearing mice by one half. Oxoplatinum--induced changes in the renal tissue ranged from moderate under continuous administration to acute renal failure after high--dose treatment. Such diuretics as diacarb, furosemide and, particularly, mannitol did not interfere with oxoplatinum activity against solid and ascites tumors but assured less pronounced structural disorders in the kidney as compared to oxoplatinum alone.

Acetazolamide↗
PubMed1990

[Oligomeganephronic renal hypoplasia complicated by glomerulonephritis].

Clinico-anatomical data of a rare condition congenital oligomeganephronic renal hypoplasia with a glomerulonephritis as a complication are available for a 13-year-old girl who died of chronic renal failure. Large aglomerular zones consisting of primitive canaliculi in a loose stroma were observed in kidneys that were decreased in size. The glomeruli were few in number, some of them of a large size (2-2.5-fold), firmly attached to the capsule, with pronounced extracapillary proliferation.

Adolescent↗
PubMed1978

[Alveolar soft tissue sarcoma].

An autopsy observation of alveolar soft tissue sarcoma of the left hip muscles in a man of 66 is described. Predominantly lymphogenic metastasizing of the alveolar sarcoma was observed and two hypes of tumour cells, "dark" and "light" were distinguished. PAS-positive substances, lipids and mucus were found in the cytoplasm of the "light" cells. Histogenetically, the alveolar soft tissue sarcoma is assumed to be close to striated muscles.

Aged↗
PubMed1977

[Malignant glomus tumor of the jejunum with distant metastases].

An autopsy observation of a malignant glomal tumor (angioleiomyomatotic variant) of rare localization (jejunum) with degeneration, outgrowth through the intestinal wall, and numerous metastases (regional, paratracheal and bifurcational lymph nodes, the liver, lungs) in a man of 65 is described.

Aged↗
PubMed1977

[Acute untreated idiopathic polymyositis with cardiac lesions].

An autopsy observation of acute idiopathic polymyositis with the involvement of the sceletal musculature and the heart in a man of 23 who had not been treated with corticosteroids is presented. The main morphological lesions were found in the cross-striated muscles and myocardium. They were characterized by deep degeneration, necrosis, and atrophy of muscle fibers, multiplication of sarcolemma nuclei, massive lymphoplasmo-histiocytis infiltration of the interstitial tissue, active resorbtion by macrophages of the dead muscle cells, the occurrence of giant cells. No disorganization of the connective tissue of the muscles, derma, and the vessels was observed.

Acute Disease↗