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Biomedical subjects

V A Trotsevich

Publications and source records attributed to V A Trotsevich.

At least 19 recordsLinked to original sources

[The use of acetylcysteine in the combined treatment of patients with acute 1,2-dichloroethane poisoning].

The authors analyse the use of acetylcysteine as specific antidote treatment in 37 patients with acute 1,2-dichlorethane (DCE) poisoning. Administration of dichlorethane did not produce any determining effect on the outcome of the treatment in critical and irreversible concentration of DCE in the blood. The main component in complex therapy is early hemosorption. Acetylcystein may be used in the complex treatment of acute DCE intoxications after early extracorporal detoxication with the purpose of reducing the severity of troxic of hepatopathies.

Acetylcysteine↗

[Hemosorption in the combined treatment of patients with acute exogenous poisonings].

The authors analyze their experience with 247 hemosorptions in 163 patients with acute exogenous poisonings. Indications and contraindications to hemosorption in these patients are described. Methodical aspects of hemosorption are described: vascular approaches, apparatus, prehemosorption care, regimens of hemosorption. Hemosorption may be associated with hemodialysis, hemofiltration, ultraviolet irradiation of the blood.

Acute Disease↗

[Hemosorption in the combined treatment of acute 1,2-dichloroethane poisonings].

Carbon hemosorption was carried out in 41 patients suffering of 1,2-dichlorethane intoxication (acute). Complex methods of therapy included also methods of potentiation of natural processes of detoxication, enterosorption, specific antidote treatment with acetylcysteine and vitamin E. Use of hemosorption favoured essential reduction of lethality, decrease of the number of severe complications (exotoxic shock, hepatopathy).

Acute Disease↗

[Tactics and emergency aid in acute chemical poisoning].

Successful treatment of acute intoxications should include early urgent measures, use of specific antidotes, polysymptomatic and polysyndromic treatment. It is an error to delay intensive care until laboratory identification of the toxicant. Only combined use of methods directed to potentiate natural urocesses, intra--and extracorporal detoxication allows to improve treatment results of treating acute intoxications.

Critical Care↗

[Cholinesterase reactivators in the combined treatment of patients with acute organophosphate insecticide poisonings].

The efficacy of different cholinesterase reactivators (alloxyme, dietixyme, dipiroxyme, isonitrosine) used as specific antidotes) was evaluated in 78 patients with acute intoxications by phosphorus-organic insecticides. The most pronounced clinical effect was obtained with use of alloxyme and dietixyme. The number of side-effects was observed during employment of dietixyme. Use of dipiroxyme with isonitrosine was less effective and was connected with a higher number of side-effects.

Acute Disease↗

[Comparative characteristics of the variants of vascular approach during performing hemosorption in patients with acute poisoning].

In performance of hemosorption in 108 patients with acute intoxications, 210 manipulations of Seldinger's central venous puncture and catheterization, Skribner's arteriovenous shunting, section of the basal brachial vein were accomplished. In 23 (10.1%) patients, the complications developed: hematoma at the site of puncture--in 10, puncture of the subclavian artery--in 3, puncture of the femoral artery--in 6, shunt thrombosis--in 2, catheter thrombosis--in 2. In patients with acute intoxications, the use of veno-venous method of hemosorption with Seldinger's catheterization of the subclavian and femoral veins is preferrable.

Acute Disease↗

[The role of hemodialysis and hemosorption in the complex therapy of acute poisoning].

The method of henosorption and hemodialysis was used in 50 patients with acute intoxication. A total of 44 hemosorption and 40 hemodialysis procedures were carried out in the toxicogenous and somatogenous stage of acute intoxication. Results indicate high efficacy of using extracorporal detoxication in the toxicogenous stage of acute poisoning. The method of treatment of acute chemical intoxications is described.

Acute Disease↗

[Changes in autonomic homeostasis during anesthesia induction in patients operated on for congenital cleft palate].

Variation pulsometry was used to study vegetative homeostasis changes over the course of induction anesthesia and tracheal intubation in children operated on for palatal clefts. The same premedication scheme was employed in all the patients. The same neuroleptic doses were administered in induction anesthesia. Induction anesthesia parallel with electroanalgesia with an Electronarcol-1 apparatus helped reduce the promedol dose necessary for adequate anesthesiologic protection from 1.2-1.4. to 0.2-0.4 mg/kg. This was associated with the minimal changes in autonomic nervous system functioning, evidencing the efficacy of electroanalgesia in induction anesthesia for this patient population.

Anesthesia, Endotracheal↗

[Variation pulsimetry as a method for assessing the adequacy of electro- and drug anesthesia in uranostaphyloplasty].

Using variation pulsimetry, the adequacy of anesthesiological management during uranostaphyloplasty has been assessed in 34 children aged 4.5 to 9 years. The studies were performed after premedication at various stages of surgery and upon extubation. Premedication, including promedol, dimedrol, droperidol and diazepam, prevented negative psychoemotional reactions in patients right before induction to anesthesia. Combined electrical and drug anesthesia performed according to a technique described above ensured good enough nociceptive protection of patients during surgery. The adaptive compensatory reactions were most pronounced in the early postoperative period.

Anesthesia, General↗

[Ontogenetic features of autonomic homeostasis in children according to the data of variation pulsometry].

A method of variation pulsometry was used to determine the vegetative homeostasis state in 20 children aged from 4 to 14. Normotonic type of the cardiac rhythm regulation was observed in a group of children aged 4-5. In children aged 12-14 the effect of sympathetic area of the vegetative nervous system decreased while the effect of the parasympathetic one increased. The tension index, effect of the humoral regulation channel and the degree of cardiac rhythm control centralization decreased.

Adolescent↗