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V A Volodchenko

Publications and source records attributed to V A Volodchenko.

27 records · Page 2Linked to original sources

[Toxicological properties of benzanthrone and its derivatives in relation to their chemical structure].

The paper presents a comparative study covering toxicological characteristics of benznthrone, brombenzanthrone, dibrombenzanthrone, methoxybenzanthrone, dibenzanronyl, dibenanthrone (violanthrone). The mentioned compounds were found to have a low acute and marked subchronic toxicity manifesting itself in the damaging action on the blood and liver. Here the reaction of the lympho-histiocytic elements along with the appearance of plasmatic and mast cells is typical. In the series of the study compounds most toxic are benzanthrone and its bromine-derivatives. Incorporation of a methoxy-group in the benzanthrone molecule and conjugation of two benzanthrone molecules help lessen the toxic action.

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