[Toxicological characteristics of xanthanic hydrogen--a new rubber vulcanization accelerator].
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Biomedical subjects
Publications and source records attributed to V A Volodchenko.
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The paper presents a comparative study covering toxicological characteristics of benznthrone, brombenzanthrone, dibrombenzanthrone, methoxybenzanthrone, dibenzanronyl, dibenanthrone (violanthrone). The mentioned compounds were found to have a low acute and marked subchronic toxicity manifesting itself in the damaging action on the blood and liver. Here the reaction of the lympho-histiocytic elements along with the appearance of plasmatic and mast cells is typical. In the series of the study compounds most toxic are benzanthrone and its bromine-derivatives. Incorporation of a methoxy-group in the benzanthrone molecule and conjugation of two benzanthrone molecules help lessen the toxic action.