Biomedical subjects

V Antolic

Publications and source records attributed to V Antolic.

At least 19 recordsLinked to original sources

PubMed2004

High contact hip stress is related to the development of hip pathology with increasing age.

BACKGROUND: High contact hip stress is believed to be one of the key biomechanical factors involved in the hip cartilage degeneration and osteoarthritis. Accordingly, with increasing age high contact hip stress is expected to cause elimination of subjects from the population of healthy hips, but its predictive value has not been evaluated so far. The objective of the paper is to investigate whether the exposure of healthy hips to estimated high contact hip stress is related to the development of hip pathology with increasing age. METHODS: A cross-sectional age- and gender-matched analysis of the peak contact hip stress calculated from pelvic geometry was made in 103 adult subjects with healthy hips. The peak contact hip stress was calculated from anterior-posterior pelvic radiographs of healthy hips by using a mathematical model of the human hip in the static one-legged stance. FINDINGS: In both female and male population, the average values of the peak contact hip stress normalized to the body weight are significantly higher and the values are also more dispersed in younger subjects when compared to older subjects. INTERPRETATION: The hip joints which remain healthy in the old age have lower average estimated peak contact hip stress. These results are consistent with the explanation that subjects with high estimated peak contact hip stress are more likely to develop hip disease in the course of life.

Adult↗

PubMed2003

Polyethylene wear in total hip prostheses: the influence of direction of linear wear on volumetric wear determined from radiographic data.

PURPOSE: To develop a new mathematical model for calculating the volumetric wear of polyethylene cups from known values of the radius of the prosthesis head, the extent of linear wear and the direction of linear wear determined from standard antero-posterior radiographs. METHOD: A new mathematical model was developed. The results of this new mathematical model were compared with the results obtained using the standard, frequently used mathematical model, which takes into consideration only the radius of the prosthesis head and the extent of linear wear of the polyethylene cups. The results of both mathematical models were further compared with the results obtained by direct measurement of volumetric wear using the fluid displacement method. RESULTS: Comparison of the mathematical models shows that the average volumetric wear calculated using the new mathematical model is 8.5% smaller than the average volumetric wear determined by the fluid displacement method, while the average volumetric wear calculated by standard mathematical model is 17.5% higher. The results of the new mathematical model are, thus, notably less biased than those of the standard one. CONCLUSION: In calculating the volumetric wear from antero-posterior radiographs, not only the radius of the prosthesis head and the extent of the linear wear but also the direction of the latter has to be considered.

Adult↗

PubMed2003

Influence of contact hip stress on the outcome of surgical treatment of hips affected by avascular necrosis.

INTRODUCTION: Biomechanical analysis is an important tool that could improve the treatment of a diseased hip. However, it is still unclear how the biomechanical status affects the clinical outcome of a certain disease. In this work we studied the long-term effect of contact hip stress on the clinical outcome of hips that were operated on by various intertrochanteric osteotomies due to avascular necrosis of the femoral head. The hypothesis being tested is that the hips with a more favourable postoperative distribution of contact hip stress have a better clinical outcome. MATERIALS AND METHODS: The study was performed on a population of 30 hips. For each hip, we determined the peak contact hip stress before the operation and immediately after the operation by using a recently developed method based on a three-dimensional mathematical model and the data from standard anteroposterior roentgenographs of both hips and pelvis. The hips were evaluated clinically 9-26 years after the operation and divided into a successful and an unsuccessful group. The average change of the peak stress due to the operation was calculated for each group, and the values were compared by t-test. RESULTS: In the successful group the operation caused an average decrease of the peak hip stress of about 10%, while in the unsuccessful group the operation caused an average increase of the peak hip stress of about 4%, the difference between the respective changes of the peak stress due to the operation being statistically significant ( p=0.001). CONCLUSION: Our results support the hypothesis that the hips with a more favourable postoperative distribution of contact hip stress have a better clinical outcome.

Adult↗

PubMed2002

Mathematical estimation of stress distribution in normal and dysplastic human hips.

By using a mathematical model of the adult human hip in the static one-legged stance position of the body, the forces acting on the hip, peak stress in the hip joint and other relevant radiographic and biomechanical parameters were assessed. The aims were to examine if the peak stress in dysplastic hips is higher than in normal hips and to find out which biomechanical parameters contribute significantly to higher peak stress. The average normalized peak stress in dysplastic hips (7.1 kPa/N) was markedly higher (to approximately 100%) than the average normalized peak stress in normal hips (3.5 kPa/N). The characteristic parameters that contributed to higher peak stress in dysplastic hips included the smaller lateral coverage of the femoral head, the larger interhip distance, the wider pelvis, and the medial position of the greater trochanter. These results are consistent with the hypothesis that stress distribution over weight-bearing surface of the hip joint is the relevant parameter for assessment of the risk for developing coxarthrosis.

Adolescent↗

PubMed2001

The assessment of contact stress in the hip joint after operative treatment for severe slipped capital femoral epiphysis.

We determined contact stress on the articular surface of the hip joint in a group of patients who underwent operative treatment for severe slipped capital femoral epiphysis. Two different procedures were considered: the modified osteotomy of Dunn-Fish and the osteotomy of Imhäuser. In order to determine the stress distribution, a three-dimensional mathematical model was used taking into account the geometrical parameters of the pelvis and hip, which were measured from standard antero-posterior radiographs. We found that the Dunn-Fish procedure produced lower peak stress than the Imhäuser procedure.

Adolescent↗

PubMed2001

Biomechanical evaluation of hip joint after Salter innominate osteotomy: a long-term follow-up study.

The biomechanical state of the hip after a Salter innominate osteotomy was investigated by using the radiographic data of 38 operated and 21 contralateral nonoperated hips from our archives. The centre-edge angle of Wiberg was determined from the radiographs taken shortly after the operation. From the radiographs of the latest follow-up (7-13 years after the operation), we also determined the peak value of contact hip joint stress normalized by the body weight, and the functional angle of the weight-bearing area. A mathematical model was used. We show that the geometrical parameters aside from the centre-edge angle may considerably influence the contact hip stress distribution. We also show that the functional angle of the weight-bearing area is a more relevant parameter than the normalized peak stress if the exact magnification of the images is not known and if there is considerable variation of the image size within the sample. The development of the centre-edge angle of the operated hips and of the contralateral hips was also studied. We found that the centre-edge angle increases on average during the follow-up time in the operated hips as well as in the contralateral nonoperated hips, but the average increase is smaller in the former. It is shown that an unfavorable stress distribution is connected to the decrease of the centre-edge angle over time. Finally, we found a weak positive correlation between the centre-edge angle shortly after the operation and the functional angle of the weight-bearing area at the of the latest follow-up.

Biomechanical Phenomena↗

PubMed2001

The effect of electrostimulation and high load exercises in patients with patellofemoral joint dysfunction. A preliminary report.

Traditional conservative treatment for patellar disorders is successful in about 80 percents of cases. We introduced two new conservative treatment protocols for patellar pathology in order to further improve the success rate. The first protocol consisted of high load/low repetition quadriceps femoris training (10 patients) while the second enclosed selective electrostimulation of vastus medialis muscle (7 patients). Results were evaluated clinically and neurophysiologically. High load/low repetition training resulted in significant increase of maximal voluntary contraction of quadriceps muscle (P < 0.001). Significant gain of Activity (P = 0.017) and Kujala scores (P = 0.07) was observed in group with high load/low repetition quadriceps training compared to patients with electrostimulation. There was no significant change in neurophysiological or clinical status between the beginning and the end of treatment with electrostimulation. Our results indicate that high load/low repetition quadriceps femoris training poses an important alternative to traditional conservative treatment protocol for patellar disorders.

Electric Stimulation↗

PubMed2001

Determination of contact hip stress from nomograms based on mathematical model.

Nomograms are presented that enable determination of maximal stress on the hip joint weight bearing area if certain geometrical parameters of the hip and pelvis and the body weight are known. The nomograms are calculated by using previously developed mathematical models. It is demonstrated how the maximal stress on the hip joint weight bearing area is determined from the presented nomograms for a hip for which the geometrical parameters were obtained from a standard anteroposterior rentgenograph. This simple and noninvasive method may give insight into the biomechanical status of the hip which should be considered in routine surgical planning and as a part of the routine examination of the patient without the use of any additional tools.

Biomechanical Phenomena↗

PubMed2001

Isolation of polyacetal wear particles from periprosthetic tissue of isoelastic femoral stems.

We analysed revised Mathys isoelastic polyacetal femoral stems with stainless-steel heads and polyethylene acetabular cups from eight patients in order to differentiate various types of particle of wear debris. Loosening of isoelastic femoral stems is associated with the formation of polyacetal wear particles as well as those of polyethylene and metal. All three types of particle were isolated simultaneously by tissue digestion followed by sucrose gradient centrifugation. Polyacetal particles were either elongated, ranging from 10 to 150 microm in size, or shred-like and up to 100 microm in size. Polyethylene particles were elongated or granules, and were typically submicron or micron-sized. Polyacetal and polyethylene polymer particles were differentiated by the presence of BaSO4, which is added as a radiopaque agent to polyacetal but not to polyethylene. This was easily detectable by back-scattered SEM analysis and verified by energy dispersive x-ray analysis. Two types of foreign-body giant cell (FBGC) were recognised in the histological specimens. Extremely large FBGCs with irregular polygonal particles showing an uneven, spotty birefringence in polarised light were ascribed to polyacetal debris. Smaller FBGCs with slender elongated particles shining uniformly brightly in polarisation were related to polyethylene. Mononucleated histiocytes containing both types of particle were also present. Our findings offer a better understanding of the processes involved in the loosening of polyacetal stems and indicate why the idea of 'isoelasticity' proved to be unsuccessful in clinical practice.

Adult↗

PubMed2001

Salter osteotomy for treatment of acetabular dysplasia in developmental dysplasia of the hip in patients under 10 years.

Serial radiographs of 44 hips in 39 patients undergoing Salter innominate osteotomy for the treatment of dysplastic acetabulum owing to developmental dysplasia of the hip were reviewed. The hips were also evaluated clinically at the last follow-up examination, 7 years to 13 years postoperatively. At 7 years to 13 years postoperative, excellent or good clinical results were assessed in 43 hips (98%), and excellent or good radiographic results in 32 hips (73%). In patients with a postoperative center edge (CE) angle > 24 degrees, the CE angle remained significantly greater throughout the follow-up period compared with patients with a postoperative CE angle < or = 24 degrees. A positive correlation was found between the degree of operative CE angle correction and radiographic findings 7 years to 13 years postoperatively.

Acetabulum↗

PubMed2000

Weight bearing area during gait in normal and dysplastic hips.

The size and the shape of the weight bearing area in adult human hips depend on the forces acting in the hip and therefore change during the body motion. In this work the size and the shape of the weight bearing area in several phases of gait are estimated. The forces acting in the hip were determined through laboratory measurements and analyzed by mathematical models. The dysplastic hips are distinguished from the normal ones by a smaller center-edge angle of Wiberg while the time course of the forces acting in the hip is assumed to be the same in both cases. It is shown how radial articular stress is distributed over the weight bearing area in both cases. In normal human hips the weight bearing area occupies a rather large portion of the acetabulum-femoral head contact area while in dysplastic hips stress distribution is unfavourably concentrated in a smaller weight bearing area.

Adult↗

PubMed2000

Biochemical aspects of Salter's osteotomy for treatment of acetabular dysplasia.

The center-edge (CE) angle was measured on serial antero-posterior radiographs of 44 hips treated by Salter's innominate osteotomy for developmental dysplasia of the hip. Radiographic examination according to Severin was performed and the peak hip joint pressure was calculated using geometrical parameters determined from radiographs at the most recent follow-up examination, 7 to 13 years postoperatively. At the latest follow-up assessment, there was a positive correlation between the postoperative CE angle and radiographic results. Negative correlation was found between the postoperative CE angle and peak hip joint pressure at the latest follow up. In conclusion, Salter's osteotomy performed to treat developmental dysplasia of the hip should involve radical acetabular correction resulting in maximum increase of the CE angle.

Acetabulum↗

PubMed2000

Different operative treatment of slipped capital femoral epiphysis: a comparative study of biomechanical status of the hip.

The biomechanical status of the hips subject to two different operative treatments was studied. The biomechanical status was determined by the peak stress on the weight bearing area using the 3-d mathematical model. It was found that the procedure according to Imhäuser yields considerably and statistically significantly higher peak stress than the procedure according to Dunn-Fish.

Biomechanical Phenomena↗

PubMed2000

Peak contact stress in human hip during gait.

The contact stress in a human hip is not uniform and it changes with different body positions. The changing location of the peak contact stress during gait may indicate the predilection sites for further development of osteoarthritis in the hip. On the basis of laboratory measurements and by using mathematical models of forces and stresses in human hip we determined the points of the peak contact stress in successive phases of gait. Results show that the peak stress points are mostly located in the posterior-medial portion of the weight bearing area, which corresponds well to the clinical observations. It is also shown that in the pathological conditions of hip dysplasia the peak contact stress trajectory is located more laterally and anteriorly.

Gait↗

PubMed2000

Evaluation of biomechanical status of dysplastic human hips.

The evaluation of the biomechanical status of human hip joint was performed. Required parameters were assessed from standard antero-posterior rentgenographs and the value of contact stress on the weight bearing area is calculated. We analysed 45 dysplastic human hips and compared measured values to 81 healthy hips. The peak contact stress on the weight bearing area is considerably and statistically significantly higher in dysplastic hips compared to healthy hips. The Wiberg centre-edge angle is statistically significantly smaller in group of dysplastic hips compared to healthy hips.

Arthrography↗

PubMed1999

Increased muscle stiffness after anterior cruciate ligament reconstruction--memory on injury?

Residual impairment of knee function was tested in 25 patients 6 to 12 months after successful unilateral reconstruction of the anterior cruciate ligament. The control group comprised 25 healthy individuals. Jumping onto one foot from a height of 20 cm was taken as a prototype of similar everyday activities. We measured maximum flexion of the knee during the landing phase of the jump, and the degree of knee flexion at the time of maximum deceleration of the knee against gravity during jumping using the three-dimensional optical motion analysis system-ELITE. In the group of patients, measured parametres were significantly smaller on the operated side than on the unaffected side. These two measured values were significantly smaller on both legs in group of patients as compared to the values in the control group. The results of our study indicate that functional disturbance persisted for 6 to 12 months after anterior cruciate reconstruction. This may be due to the changed muscle activation pattern of the knee causing increased stiffness of knee muscles. It seems that re-programming of the central nervous system occurred in order to protect the injured lower extremities from another injury.

Adolescent↗

PubMed1999

[Anterior cruciate ligament function: a non-invasive quantitative technique].

PURPOSE OF THE STUDY: The purpose of the study was to develop a new non-invasive and quantitative method for evaluation of the anterior cruciate ligament function. PATIENTS AND METHODS: The new method was tested in 24 asymptomatic subjects and in 58 patients (39 males and 19 females) with arthroscopically proven unilateral rupture of the anterior cruciate ligament. Anterior displacement of the tibia with the knee in 20 degrees flexion was achieved by using a redesigned device, constructed originally for stress-radiography, and detected by a 3-D optical motion analysis system. RESULTS: In the normal group, the average difference (d) in anterior displacement of the tibia between the left and the right side under a displacement force of 250N was 0.56 mm (range 0.1 mm to 1.9 mm) or 17 p. 100 (range 2 p. 100 to 64 p. 100), while in patients the average difference (d) in anterior displacement of the tibia between the injured and uninjured side under a displacement force of 250N was 4.02 mm (range 0.6 mm to 9.4 mm) or 133.6 p; 100 (range 26 p. 100 to 451 p. 100). By the criteria for false negative results, i.e. the maximum value of the parameter d in normal subjects (1.9 mm and 64 p. 100), 10 p. 100 of the patients (6 patients) fell into the normal group. According to the criteria of false positive results, i.e. the minimum value of the parameter d in patients (0.6 mm and 26 p. 100), 17 p. 100 of the normal subjects (4 normal subjects) fell into the group of patients. The achieved level of differentiation is in the similar range as the most frequently used present methods. DISCUSSION: The main advantage of the newly developed noninvasive optical measurement technique is that the direction of force and the amplitude and site of application are accurately defined and documented, and that dislocation movement of the tibia towards the femur during the application of a growing force is continuously monitored with the 3-D optical system and that it allows for several consecutive assessments based on statistical data.

Adolescent↗

PubMed1997

Increased incidence of arthrosis in women could be related to femoral and pelvic shape.

In this study various femoral and pelvic geometrical parameters important for hip joint contact stress were determined. The parameters were measured from standard anteroposterior radiographs of healthy adult subjects and analysed by using descriptive statistical procedures. Women proved to have a significantly smaller femoral head radius and larger distance between the inner acetabular rims than men, both features which lead to an increase of contact stress in the hip joint articular surface. Since too high, long-lasting contact stress is unfavourable regarding the development of arthrosis, we propose that these differences in the femoral and pelvic geometry could be one of the reasons for the increased incidence of arthrosis in women.

Adult↗