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Biomedical subjects

V Astărăstoae

Publications and source records attributed to V Astărăstoae.

At least 19 recordsLinked to original sources
PubMedDate not supplied

[Myocardial bridging and sudden death].

Myocardial bridging (MB) has been described more than 200 years ago. However it's implications on the genesis of myocardial ischaemia were not studied until recently. Little is known about the real incidence, survival in people with this entity and pathophysiology. Data found in the literature are prone to bias since all studies published are retrospective and the populations studied are limited and very selectioned. Most authors agree that most MB is rather frequent and seldom generates ischaemia. A significant clinical effect of myocardial bridging implies a thick MB with at least 75% coronary systolic obstruction associated with ventricular hypertrophy and/or rapid tachycardia. In the peculiar case of sudden death, we think that to consider MB as a cause of this sudden death we need more than a simple necroptic finding of a MB. A history of clinical and/or electrocardiographic confirmed ischaemia or the presence of histological abnormalities suggesting myocardial ischaemia can be helpful.

Coronary Angiography↗
PubMedDate not supplied

Etio-pathogenic views on transsexualisms (TS).

Starting from the analysis of six cases of transsexualism (TS) the authors performed complex investigations of all sex levels and identified primary T.S. (disturbances of sexual differentiation), secondary TS (sexual perversions, sexopathy). This distinction appears to the authors as unavoidable for ethico-pathological and legal drive in view of the implications of T.S.--implications able to be analysed from standpoint.

Adult↗
PubMedDate not supplied

[Hypertrophic cardiomyopathy--cause of sudden death].

Hypertrophic cardiomyopathy (CMH) is defined by the absence of left ventricular dilatation and the presence of myocardial hypertrophy that is not due to another recognised cause of hypertrophy such as systemic hypertension or aortic stenosis. The bizarre histological appearance of the myocardium is the hallmark of CMH. Myocytes and bundles of myocytes are malaligned and fibrosis may be extensive. Disarray is maximal in areas of macroscopic wall thickening. The condition is most easily recognized in a series of transverse, short axis slices across both ventricles. Histological examination of sections taken in this transverse plane at all three levels (high, mid, apical) including septum, anterior, posterior and lateral walls are needed. The authors report a case of cardiac sudden death to a 45 years old white man. The diagnosis was revealed intra vitam and it was confirmed post mortem.

Cardiomyopathy, Hypertrophic↗
PubMedDate not supplied

[Arrhythmogenic right ventricular dysplasia].

Arrhythmogenic right ventricular dysplasia (ARVD) is a new form of cardiomyopathy probably more frequent than commonly reported. The incidence is unknown. ARVD is a heart muscle disorder of unknown cause that is characterised pathologically by fibro-fatty replacement of the right ventricular myocardium. It is a rare but important cause of sudden cardiac death in young, otherwise healthy persons. The right ventricle should be extensively sampled histologically in all cases of sudden unexpected death, especially those that are exercise related. The disease is often familial (about 30%) with an autosomal dominant inheritance.

Arrhythmogenic Right Ventricular Dysplasia↗
PubMedDate not supplied

Sociopathy: genesis and development.

A complex study of a sample of 1,029 children and young people cared for in orphanages revealed the increased incidence of the disorders of behaviour in these categories (33%) with great difficulties of post-school integration (70%). Factors like: affective frustration, noxious family climate intellectual handicap, socializing defect, school failure, etc. are deeply involved in the genesis of juvenile maladjustment and it further on can be found within the nucleus of the sociopathic personality and in adult's deviance.

Adolescent↗
PubMedDate not supplied

[Integrative model of the ontogeny and destruction of human behavior].

In a review of the data in the literature completed with authors own researches (concerned with twins, chromosome abnormalities, incestuous descent, socially assisted children etc.) an integrative model regarding the ontogenesis and destruction of human behaviour is presented. According to this model, behaviour appears as a hierarchical and integrated system expressing the process of its development from automatic and reactive to noologic and reflexive. The integrative, systemic concept promotes, theoretically and methodologically, the understanding and competent investigation of human behaviour in its two fundamental states, integrated and destructive.

Behavior↗