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Biomedical subjects

V B Ushakov

Publications and source records attributed to V B Ushakov.

At least 19 recordsLinked to original sources

[Physiological model of the stabilizing form of natural selection at the cellular level].

By means of directional elimination of the parental gametes in frogs, the effects of two basic forms (i.e. normalizing and canalizing ones) of natural selection on the heat resistance level of muscle fibers in the progeny have been reproduced. Experimental evidence is presented that both male and female gametes account for hereditary transformation of cellular heat resistance as a quantitative physiological parameter. Polymodal pattern of regulation of this parameter is suggested which includes indispensable participation of both thermal and non-thermal factors of selection. The environmental temperature, as a selective factor, accounts for the formation of cellular heat resistance directly, whereas non-thermal factors exert their control on this parameter indirectly, associatively. It is suggested that the polymodal pattern of regulation of physiological functions presents the main mode of realization of canalizing form of natural selection.

Animals

[Hereditary effects of artificial selection of sperm for the endurance trait in the carp Cyprinus carpio and the frog Rana temporaria].

Studies have been made of the effect of artificial selection of parental sperm by maximum motility time (maximum tolerance) on the body length in carp larva and heat resistance level of muscle tissue in tadpoles. Sperm selection increases mean values of these parameters due to the increase in the progeny of the relative number of long-sized individuals and individuals with higher heat resistance of muscle fibers.

Animals

[Trophic influence of the nervous system on the heat resistance of skeletal muscles in rats].

Chronic denervation of m. extensor digitorum longus in rats significantly increase the heat resistance of muscle fibers. This effect does not result from muscle disuse, since tenotomy does not affect the level of heat resistance of muscle fibers. After bilateral adrenalectomy, the thermostability of muscles remains unaffected. The data obtained are discussed in relation to the problem of coupled changes in thermostability and electrogenesis of muscles fibers in animal evolution.

Adrenalectomy