Biomedical subjects
Publications and source records attributed to V Bíró.
Authors describe the cases of two patients, suffering from the rare, however frequently not diagnosed real writing spasm. In these patients surgery brought healing or significant improvement. After a review of the literature the symptoms, the possibilities of diagnosis and therapy are described. With their paper they want to call attention to this not well known disease.
Authors have compared two kind of exposures of the flexor tendons. The results were assessed by measuring the flexion oft the given finger on pulling, by light and electron microscopic examination. It was found that in fingers where the tendon sheat was detached from the subcutis the scarring was greater and its effect, limiting the motion has its maximum on the fourth postoperative week. It is raised that the role of the tendon sheat in respect of the success of the flexor tendon reconstruction is mainly mechanic and most effective if its highly integrated connection with its surrounding is not disturbed.
Authors report on clinical experiences gained with the two stage flexor tendon transplantation described by Hunter. Their modifications are described and the results given in details. They touch also upon the indications of the procedure considering the preoperative evaluation. Other procedures are also offered for injuries with bad prognosis and the future trends of investigation, held to be important, are mentioned.
Authors have investigated the ultrastructure of the pseudo tendon sheath, formed with silicon rod and man. They have observed a superficial structure, resembling the normal tendon sheath in scanning electron microscopic examination. With transmission electron microscopy phagocyte "A" type and secretion "B" type synovial cells were found. Authors state that the newly formed tenosynovium has an important role in the nutrition of the tendon graft and the prevention of adhesions.
Authors suggest, in their paper, a new method in this country, the so called brace treatment for the functional treatment of the diaphyseal fractures of the humerus. A 2-4 fifth of the diaphyseal fractures of the humerus can be treated in the majority with this method. An other novelty of this treatment is the humerus brace developed and manufactured in Hungary. This fracture treatment has unequivocal advantages both for the health service and the patient for its shorter duration of healing and treatment.
Authors discuss, based on the experiences of their 18 cases, the injuries of the knee extensors. 5 ruptures of the quadriceps and 9 of the lig. patellae propr. were observed in the 14 cases controlled. Based on their own experiences and the standpoints of the literature they suggest the operative therapy within 6 hours in the open injury and within 1-5 days following the accident in closed cases. The experiences, the operative technique, the viewponts of the aftercare and the end results are described.
Authors, based on the experience gained from the operative therapy of a 9 year old child with inveterated Monteggia injury, discuss the types, the diagnosis and the principles of treatment of this injury. They take the part of urgent treatment following early diagnosis as the results of the treatment of the non-fresh cases are generally less favourable.
Author reports on the experiences with the operative treatment of 48 acetabular fractures in his Department during 19 years. He thinks that the operative treatment of the acetabular fractures may be successful only after the exact preoperative diagnosis and classification of the type of the fracture. After this the exposure may be chosen. During the operation one has to strive to the exact reconstruction of the articular surfaces and the performance of such stable osteosynthesis that will enable the early movements of the joint without weight bearing. If, because of the severity of the injury, the exact reconstruction of the acetabulum is not possible an effort must be made to create an anatomical situation that will give favourable conditions to late reconstruction operations (arthrodesis or endoprosthesis). Author describes after discussing the classification, diagnosis and treatment of the acetabular fractures his own results: in more than 3/4 of his cases excellent or good late results could be achieved. For this, with correct indication, the performance of the reconstruction operation is suggested.
Authors discuss, based on the experiences gained in the operative treatment of posterior sternoclavicular dislocation in two patients, the frequency, the symptoms, the classification, the diagnosis and treatment of this rare injury. One of the two injuries was fresh the other inveterated. No description of the operative treatment of similar injuries was found in the literature of this country. Finally the importance of the early recognition and the definitive treatment of this rare dislocation are stressed.
Authors describe the operative method of Iselin for the treatment of inveterated extensor tendon injuries over the DIP joint and their results. On the basis of favourable experiences they suggest the use of this method. No description of this procedure was found in the literature of this country.
After a short literary review authors analyse the clinical and pathological process of the traumatic fat embolism. They call attention to the difficult diagnosis of the syndrome and to its frequency. The demonstration of the fat globuli from the peripheric blood is suggested by the authors who perform this as a screening for an easier diagnosis--if characteristic clinical symptoms are also joined to the microscopic finding.
Authors examined in a 15-year material of the Department of Traumatology, Clinic of Surgery of the Pécs University of Medicine the late results of Bennett's fracture, treated surgically. In the treatment of 51 patients they came to the conclusion that the reduction of the fracture with anatomical exactness and the early functional treatment improved the results considerably.
Authors use since 1982 the mini fixateur externe in the treatment of the severe infected injuries of the hand. The stable, external fixation resulted in all the 31 patients, treated unsuccessfully with other methods, in healing.
The authors discuss the use of tendon grafts, primarily in flexor tendon repair, a problem not yet satisfactorily resolved. Criteria for successful non-autogenous tendon grafts are presented, with interest focussing on the immunologic antigenicity of the grafts and the physiologic properties and processes of tendon regeneration. Methods for preserving tendon grafts, including freeze-drying and the use of various chemical agents, are compared and recommended, as well as methods for managing tendon grafting procedures. Questions remaining to be answered in the area of preserved tendon grafts are raised, with suggestions for some answers and avenues for future research. Possibilities for wider clinical applications of the procedure are supported and discussed as well.
The specific competitive alpha 1-postsynaptic blocking action and haemodynamic effects of prazosin (Minipress) have been summarized. Prazosin causes dilatation of arterioles and veins, reduces total peripheral resistance as well as preload and afterload. Cardiac output does not change at rest, stroke volume and subsequent cardiac output increase during exercise. The changes in heart rate have non-significant. It does not cause sympathetic counter-regulation, plasma renin activity does not increase, aldosterone level decreases, salt- and fluid retention may rarely be observed. It does not provoke angina. The authors report on the results of their examinations with the first dose of prazosin in 61 patients (in 33 cases by the double-blind cross-over method by placebo control), and summarize the observations made with the drug in long-term treatment in Hungary. The authors and other teams used prazosin as a long-term treatment (of approximately 3 months) in combination with other drugs in a total of 344 patients, and as monotherapy in 159 patients. In the course of combination treatment side-effects were observed in 15% of the patients (dizziness, headache, weakness, occasionally palpitation). During monotherapy, side-effects occurred in 12% of the patients (tachycardia, headache, weakness, dizziness). Hungarian results confirm the usefulness of prazosin in all stages of hypertension. It is effective in 30-35% of the cases as a monotherapy (this rate is congruent with the efficacy of beta-blockers, calcium antagonists and antihypertensive drugs of central action). Earlier prazosin had been used as a third agent in combination treatment of hypertension.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors give a short description, based on own experimental work and literary data, of the tendon sheat biomechanics of the long fingers. The importance of the integrity of the tendon sheat--subcutis--skin unit is presented. Starting from this, a new possibility of exposing the flexor tendons, a laterobasal exposure is shown. The experimental character of their work is stressed, it is however underlined that clinical importance is attached to their aspect.
Twenty patients with moderate (4) to severe (16) hypertension, whose blood pressure (BP) could not be controlled on the previous combined antihypertensive therapy, were investigated. In acute studies the first doses of captopril, 25 and 50 mg led to a significant drop in BP 30 min after administration. The maximum fall in BP was recorded at 90-120 min and this effect was maintained throughout the whole observation period (8 hours). The fall in BP was similar in supine and standing positions and there was no change in the heart rate. During long-term (14.5 months) therapy only 2 out of the 20 patients exhibited continuing good BP control with captopril monotherapy of a maximum daily dose of 150 mg. A comparison of the acute and chronic BP lowering effects of captopril showed that the first dose of captopril caused a significantly greater decrease in BP than chronic monotherapy. However, combined captopril with a diuretic or with a diuretic and calcium antagonist or beta blocker provided a sustained BP control, significantly better than the previously used anti-hypertensive combinations (182 +/- 27/115 +/- 11 mmHg vs 164 +/- 20/104 +/- 11 mmHg p less than 0.05). The Hungarian captopril preparation (Tensiomin), similarly to other captopril products, through its angiotensin converting enzyme inhibition, caused an increase in plasma renin activity and in concentration of plasma angiotensin I and a decrease in plasma angiotensin II. Eight out of the 20 patients developed side effects, which disappeared spontaneously in 4 patients within 2-14 days. Captopril was withdrawn in 3 patients for not achieving satisfactory BP control and/or because of side effects. It is concluded that captopril is safe and effective in the long-term treatment of hypertension, however, majority of the patients with severe forms of hypertension required double or multiple combinations.
Explore the source record for details and available documents.