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Biomedical subjects

V Balasubramaniam

Publications and source records attributed to V Balasubramaniam.

At least 19 recordsLinked to original sources

Stereotactic cingulumotomy for drug addiction.

This paper analyzes the results of surgical treatment of 73 patients with drug addiction. They were treated by lesions in the anterior cingulum. Morphine, Pethidine (meperidine) and alcohol were the common drugs of addiction. Selection of cases, rationale for surgery and operative technique are discussed. Follow-up varied from 1 to 6 years. Results of surgery indicate this procedure as the most promising one for cure of drug addiction.

Adult

Stereotactic surgery of the limbic system in epilepsy.

During the routine follow-up of results of stereotaxic surgery in the patients treated for behaviour disorders, it was found that some of them had a bonus relief from seizures, Out of 260 amygdalotomies, 54 hypothalamotomies and 5 thalamolaminotomies performed for behavioural problems, 107 patients suffered from associated seizure disorder. 76 of them (71%) showed considerable relief from seizures following surgery. This is detailed. It is hypothesized that probably these nuclei of the "limbic system" either initiate and/or propagate seizure activity. This view is supported by the "improvement" in EEG in addition to the clinical improvement seen in these patients.

Amygdala

Why hemispherectomy?

A series of ten cases of infantile hemiplegia with behaviour disorders and with of without fits treated by unilateral stereotactic amygdalotomy is described. Out of the eight cases with fits good releif was seen in six and amelioration of the seizures in two. The behavioural disorders were well controlled in all the patients. When this procedure is compared with hemispherectomy, it is felt that operation of stereotactic amygdalotomy can be done as the procedure of first choice. Some hypotheses have been advanced to explain the modus operandi of the operation.

Adolescent