[Current treatment of renal osteodystrophy in children].
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Biomedical subjects
Publications and source records attributed to V Baudouin.
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When the eye saccades to eccentric word targets, it tends to land in a position which can be described as the center of gravity of the configuration. By manipulating the relative intensity of the word-initial and -ending letters, it was shown that the 'global effect' of luminance distribution within words is strongly attenuated when the word-initial letters are informative and orthographically irregular. Results show that the orthographic structure of the word-initial letters exerts an influence on the saccadic computation that may cancel the luminance distribution effect.
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This study was undertaken to define the pharmacokinetics of omeprazole in children and included 13 patients, heterogeneous in terms of age (0.3 to 19 years), underlying disease and biological constants, indication of omeprazole administration and associated therapy. The dose administered ranged from 36.9 to 139 mg.1.73 m-2. The pharmacokinetic parameters of omeprazole were: systemic clearance, 0.23 l.kg-1.h-1; volume of distribution, 0.45 l.kg-1; elimination half life 0.86 h; but were highly variable between individuals. Dosage, differences in hepatic and renal function and associated therapy may contribute to inter-individual variability. Within the range of doses administered, the pharmacokinetic parameters were similar to those reported in adults. The drug has been well tolerated in all children.
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