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Biomedical subjects

V Bellini

Publications and source records attributed to V Bellini.

15 recordsLinked to original sources

Double pi(0) Photoproduction on the Proton at GRAAL.

The double pi(0) photoproduction off the proton has been measured in the beam energy range of 0.65-1.5 GeV. The total and differential cross sections and the Sigma beam asymmetry were extracted. The total cross section measured for the first time in the third resonance region of the nucleon shows a prominent peak. The interpretation of these results by two independent theoretical models infers mostly the selective excitation of P11- and D13-nucleon resonances.

Journal Article↗

[Metaplastic tumors of the breast: a case of primary squamous cell carcinoma].

We report a case of primary squamous cell carcinoma of the breast in a 58 years old woman. The diagnosis of this rare tumor is possible after excluding a skin primary lesion or an epidermoid cancer of a distant site. In reviewing the reported cases we didn't find any significant prognostic difference between this form and the breast adenocarcinoma with squamous metaplasia.

Breast Neoplasms↗

[A case of primary non-Hodgkin lymphoma of the breast].

Primary non-Hodgkin's lymphomas (NHL) of the breast represent less than 3% of extranodal NHL; in comparison to extranodal NHL at other sites, they are characterized by rapid progression and worse prognosis. We report a case of primary NHL of the breast treated, after surgery, with a sequential combination of chemotherapy and radiotherapy. Literature data suggest that the most important factors in therapeutic decisions making are the initial stage of the disease and the histological subtype.

Adult↗

[Differentiated thyroid carcinomas].

Differentiated thyroid carcinomas are TSH-dependent tumors induced by genetic and environmental factors. They may be found on 3-12% of single thyroid lesions. Females are more affected than males (F:M 3:1). The combined action of genetic and environmental factors induces the development of these tumors. The cornerstone of diagnostic evaluation is Fine Needle Aspiration (FNA). Size tumors > 2.5 cm and age > 45 aa are unfavorable prognostic factors. Radical surgery is the first choice therapy followed by hormone suppressive therapy and/or I131. Follow-up is based on WBS and serum Tg evaluation. Moreover recombinant TSH offers a new approach in the field of relapse diagnosis and therapy.

Carcinoma↗

[Anaplastic, insular, and medullary carcinoma of the thyroid].

Anaplastic carcinoma, insular carcinoma and medullary carcinoma (both familiar and sporadic forms) represent the 7-25% of all thyroid tumors. Anaplastic carcinoma is one of most aggressive human tumors and the therapeutic options proposed have failed to improve the prognosis of these patients. Insular carcinoma is a not well known thyroid neoplasia described for the first time in 1984 and showing intermediate biological behaviour between differentiated and anaplastic forms. Medullary carcinoma arises from parafollicular"C" cells of the gland and then may be considered a neuroendocrine tumor. Choice therapy is surgery, tiroxine is only substitutive, familiar screening is mandatory. Chemotherapy (dacarbazine or cisplatin and doxorubicine), radiotherapy and recently octreotide anologues, may be useful for relapsing not operable forms.

Adolescent↗

[Features of primary structure of genes and proteins from passaged variations of measles virus].

Primary structure and proteins of measles virus variants passaged in tissue culture were studied. The findings suggest that genetic determinants responsible for measles virus attenuation are not linked with the genes coding for envelope proteins and nucleoprotein of this virus. However the detected nucleotide substitutions can be considered as the main prerequisites for the appearance of mutations in other regions of viral genome, leading to decrease of virulence for humans.

Amino Acid Sequence↗

[Comparative study of the nucleotide sequence of the gene for the P/C wild strain or L-16 vaccine strain of measles virus].

Nucleotide sequences of P/C gene of measles virus IL wild strain and L-16 vaccine strain were compared with the previously reported nucleotide sequence of Edmonston vaccine strain P/C gene. The primary structure of IL strain P/C gene was characterized by two substitutes in 395 (U-C) and 722 (G-A) positions in comparison with the primary structure of a similar Edmonston strain. Nucleotide sequence of L-16 vaccine strain P/C gene differed from the similar sequence of Edmonston vaccine strain by 3 substitutes in 90 (A-G), 399 (U-C), and 448 (U-C) positions. Comparative analysis of nucleotide substitutes in the P/C gene of L-16, IL, and Edmonston strains indicates that the mutations revealed in the L-16 strain P/C gene are not caused by the strain attenuation, but merely reflect the difference between the strains.

Animals↗