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Biomedical subjects

V Boccardi

Publications and source records attributed to V Boccardi.

17 recordsLinked to original sources
PubMed1977

Mycoplasma pneumoniae infection complicated by paroxysmal cold hemoglobinuria with anti-P specificity of biphasic hemolysin.

A 7-year-old boy with Mycoplasma Pneumoniae infection complicated by transitory paroxysmal cold haemoglobinuria (PCH) is described. The Donath-Landsteiner-antibody exhibited anti-P specificity; hemolytic activity was partially inhibited against papainized erythrocytes at 0 degrees C incubation temperature and increased from 8 degrees C upwards. The association of Mycoplasma pneumoniae infection with PCH has been described 4 times only and in one instance where specificity was stated it was anti-I.

Child↗
PubMed1975

Cold-haemagglutinin disease with an autoantibody exhibiting different specificities at different temperatures.

A case of chronic cold-haemagglutinin disease is reported in which an agglutinin apparently carrying two specificities was present. At first, specificity was anti-not-I and anti-I respectively: in the course of time anti-I was replaced by anti-A-1. Both anti-I and anti-A-1 could be demonstrated at room temperature only while specificity was anti-not-I at 4 degrees C. The antibody displayed haemolytic activity at room temperature and gave stronger reactions when treated biphasically. The same pattern of specificity was apparent in haemolysis tests, i.e. anti-not-I in the biphasical reaction 4 degrees C goes to 37 degrees C and first anti-I and later anti-A-1 at room temperature and at 22 degrees C goes to 37 degrees C. Anti-A-1 was not neutralized by A bloodgroup substance of animal origin nor by secretor saliva.

ABO Blood-Group System↗