PubMed Health⌕ Search

Biomedical subjects

V Costinescu

Publications and source records attributed to V Costinescu.

At least 19 recordsLinked to original sources

Therapeutical aspects of the plasmocytoma localized at the level of head and neck.

The authors present a study on 7 cases of extramedullary plasmocytoma localized in E.N.T. area, hospitalized and solved in the E.N.T. Department of the the "Sf. Spiridon" Universitary Hospital, in the last 15 years, between 1983-1997. We insist on the last solved case, presenting a double isolated localization, a laryngeal and a rhinosinusal one. We consider that the most indicated treatment in the isolated extramedullary plasmocytoma, is the radiosurgical therapy with a good rate of survival.

Aged↗

[The surgical importance of the thyro-laryngo-pharyngeal lymphatic interconnections].

The paper presents a study of the evolutional morphogenetic stages of the lymphatic and conjunctive neck structures formation. The authors make particular appreciations concerning the pattern of organization and also, the functional connections of lymphatic and conjunctive elements at intravisceral, perivisceral and perivascular level. Our study proves that these structures form the barriers but also, the spread pathways of the tumoral and inflammatory process which, after an endocavitary development, diffuse either on the adjacent organs or to the main cervical lymph nodes. We emphasized the importance of these anatomical structures in the neck oncological surgery.

Cadaver↗

[Clinical and evolutive considerations on rhinosinus cylindromas].

With reference to 7 cases of rhinosinusal cylindroma, rarely, encountered at this level (approximately 3% of all malignant rhinosinusal tumours), the authors discuss the evolution of the tumour and its treatment in the light of recent published data and their own experience in cases followed up over a long interval. In contrast to the pathohistologic aspect according to which these tumours are relatively benign, cylindromas appear to be malignant tumours with a slow, infiltrative evolution and a marked tendency to recurrence. After many years they may be transformed into carcinomas. They seldom give metastasis to the regional lymph nodes, but often generalize in the end stage by haematogenic route (with localizations in the lungs, pleura, brain, spinal column, ribs, long bones). As they are radioresistant, initial broad surgical excision is compulsory followed--when surgery is performed in the advanced stages--by complementary radiotherapy (intracavitary cobalt, intracavitary contact roentgentherapy, telecobalt, teleradiumtherapy, electron therapy).

Adult↗