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Biomedical subjects

V Cuk

Publications and source records attributed to V Cuk.

At least 37 records · Page 2Linked to original sources
PubMed1994

Ultrasonic evaluation of benign and malignant nodules in echographically multinodular thyroids.

In 165 patients with ultrasound findings of multinodular thyroids in whom thyroid resection was performed, sonographic features and pathohistologic findings of removed nodules were analyzed. Of 426 nodules removed, 70 were carcinomas and 356 benign. Carcinomas are more often hypoechogenic (p < 0.01) and contain nodular calcifications (p < 0.01), while benign nodules are more often iso-hyperechogenic (p < 0.01), showing intranodular cystic degenerative changes (p < 0.01) and perinodular hypoechogenic rim (p < 0.01). Mean diameter of carcinomatous nodules is lower than in benign nodules (p = 0.022). The relative proportion of malignant nodules is highest in the upper halves of thyroid lobes (p < 0.01). Although certain sonographic signs increase the likelihood of a given lesion being malignant or benign, the lack of absolute specificity in the ultrasound evaluation of thyroid nodules was confirmed.

Adenocarcinoma↗
PubMed1993

Lipid-bound sialic acid, prostaglandin E and histamine in head and neck cancer.

Blood concentration of lipid-bound sialic acid (LBSA), prostaglandin E (PGE) and histamine were determined in 37 patients with carcinoma of hypopharynx and larynx (supraglottic and glottic), in 12 non-cancer patients and in 10 healthy subjects. The concentration of LBSA was significantly increased in 94.4% cancer patients preoperatively and fell to somewhat lower levels within 1 month after tumour resection. In patients with complete tumour resection and no tumour recurrences within 2 years, it steadily decreased thereafter, reaching normal levels within 6-24 months after surgery, whereas in patients with tumour recurrences or incomplete tumour resection it rose again within 6 months after tumour resection. Similarly, the concentration of PGE was significantly increased in about two thirds of cancer patients (67.6%) preoperatively, dropped significantly within 1 month after tumour resection and rose again in patients with tumour recurrences. Preoperative histamine concentration was decreased in 24.3% of cancer patients and postoperatively it rose both in patients with or without tumour recurrences.

Adult↗
PubMed1992

Prognostic significance of plasma prostaglandin E concentration in patients with head and neck cancer.

Plasma prostaglandin E (PGE) levels were determined by radioimmunoassay in 53 patients with various stages (II, III, and IV) of hypopharyngeal and laryngeal squamous cell carcinoma, in 12 non-cancer patients and in 10 healthy volunteers. The mean PGE concentration was somewhat higher in non-cancer patients (mean +/- SD = 34.6 +/- 5.37 pg/ml) than in healthy subjects (28.1 +/- 4.96 pg/ml). In spite of a high data variability, the mean preoperative PGE levels in cancer patients were proportional to the stage of the disease and higher than in non-cancer patients (41.2 +/- 19.7 pg/ml, 52.8 +/- 26.7 pg/ml and 82.0 +/- 34.9 pg/ml in stages II, III and IV respectively). The mean plasma PGE concentration significantly decreased for all tumour stages 15-30 days after surgical removal of the tumour, but rose again in some patients within 6-18 months after surgery. The incidence of tumour recurrences 6 and 18 months after surgery was significantly higher in patients with an increased preoperative PGE level (greater than 43.3 pg/ml) than in those patients with a PGE level within the normal range (less than 43.3 pg/ml). The mortality was also higher in the former group, but the difference did not reach the level of significance. Similarly, the mean preoperative and most postoperative concentrations of PGE were significantly higher in patients in whom tumour recurred within 18 months than in tumour-free patients.

Adolescent↗
PubMed1988

Evaluation of the new type of military bullet and rifling.

The 5.56-mm caliber SS 109 projectile was fired from 7.7'' and 12'' twist rifles, respectively, into soap blocks and porcine thighs at 50-metre range using a standardized experimental setup. For comparison, the effects of the 5.56-mm M 193 bullet fired from the 7.7'' twist barrel and M-16 assault rifle were tested. The volume of residual cavity in soap, the shape and sizes of live tissue wounds, and the mass of surgically debrided devitalized tissue were measured. The effects of the two projectiles at 7.7'' twist were found similar in soap; the SS 109 produced more tissue damage than the M 193 missile. Using the 12" twist rifle, a significant increase in wounding capacity of SS 109 projectile was found. In conclusion, nonsignificant differences in local effects between the two projectiles using the 7.7'' twist rifles were found, and markedly increased effects of the SS 109--12'' system were ascribed to decreased essential stability and its earlier tumbling in penetrating a target. The soap as a live tissue simulant has proven its reliability in testing small-caliber arms.

Animals↗
PubMedDate not supplied

[Surgical treatment of toxic adenoma].

In the period ranging from 1985. to 1994. a total number of 86 patients have been treated for toxic adenoma (TA). Hyperthyroidism was more often present in males (70.83% versus 51.61%) and in enlarged adenomas (more then 2 cm in diameter). Pathohistologic type of adenoma influenced degenerative changes. Three carcinoma have been observed, two papillary and one follicular. Surgical treatment is the method of choice. Complications are rare (3.49%) and mild.

Adenoma↗
PubMedDate not supplied

[Adhesive ileus caused by a peritoneal reaction to starch].

Peritoneal reaction caused by glove powder is not so rare in surgical practice. We have presented a case report of a patient who was operated on due to the adhesive bowel obstruction, two years after the total gastrectomy for gastric cancer. Changes found on the peritoneal surface were similar to carcinomatous dissemination, but intraoperative frozen section analysis showed granulomatous lesions caused by foreign bodies. Nature of these changes was confirmed by PAS smear and polarization microscopy. Clarification of the peritoneal changes during relaparotomy is possible only with careful microscopic analysis of these granulomas.

Gloves, Surgical↗
PubMedDate not supplied

[Cystic mesothelioma of the greater omentum].

Peritoneal cystic mesothelioma is very rare clinical entity, and only a few cases situated on the greater omentum are described. The authors here presented two cases of the greater omentum cystic mesothelioma that were diagnosed in 260,000 adult patients hospitalized for the first time, during the fifteen year period. Cystic tumor of 30 cm in diameter was found in a 78 years old male patient, and the second one was 35 cm in diameter in female patient 56 years old. Symptomatology was not characteristic. Peritoneal pseudocyst or parasitic, lymphogen, urogenital, enteric or dermoid cyst origin was preoperatively excluded, and correct diagnosis was established upon the operative findings and immuno-histochemical investigations. In both cases keratin and vimentin were clearly positive in tumor cells, but other markers were negative (EMA, Actin, S-100, NSE, chromogranin and sinoptophysin). Cystic mesothelioma was not infiltrative and surgical treatment was simple and successful.

Aged↗
PubMedDate not supplied

[Complications in omentopexy and personal experience with 100 omentomyelopexies].

Abdominal and general complications of omentomyelopexies are seldom seen, and were mostly presented as the case reports. The aim of this study was to present in a comprehensive analysis of the data acquired from literature the reported omentopexy complications, and to compare them with our own results of the application of the omental flap with left gastroepiploic blood vessels. Prospective clinical research included the first 100 operated patients with injuries on different spinal cord levels. In all patients the omental flap was prepared by our original surgical technique and led to the site of the spinal cord lesion. In 6 of our patients we noticed seven complications and those were: three iatrogenic pneumothoraxes, two lesions of the spleen (without splenectomy), one pneumonia and one mild infection of the laparotomy wound. Prevalence of the complications related to the abdominal act of omentomyelopexy of 7% was significantly lower than in those presented in the literature with other right gastroepiploic artery omentopexies (20-79%). In our patients complications occurred earlier, lasted shorter and had no permanent implications for the patients' health. By using the omental flap with left gastroepiploic blood vessels it was possible to perform effective, relatively simple and safe omentomyelopexy for the injuries on all levels of the spinal cord. Such a mode of omental flap preparation with left gastroepiploic blood vessels could be applied for other omentopexies as well.

Adolescent↗
PubMedDate not supplied

[Clinical evaluation of serum elastase-1 levels in patients with acute pancreatitis].

The prospective examination and quantitative determination of concentration of serum elastase 1 using RIA method were performed in 75 patients with pancreatic diseases at the Clinic of General and Vascular Surgery and the Institute of Nuclear Medicine of the M.M.A. in the period 1988-1989. The values of serum elastase 1 concentration were compared with values of amylase in serum and urine. The greater diagnostical importance of serum elastase 1 was found compared to values of amylase in serum and urine, not only in patients with acute pancreatitis but also in exacerbation of chronic pancreatitis. The level of serum elastase 1 concentration enables more reliable follow up of the evolution of the disease and therapeutical effects in patients with acute pancreatitis.

Acute Disease↗
PubMedDate not supplied

[The site for esophageal transection in the treatment of hemorrhage from dilated esophageal veins].

Esophageal stapler transection was performed in 15 patients with bleeding from the dilated esophageal veins in the period 1984-1988. In 7 patients operated on as urgent cases due to prolonged uncontrolled bleeding, the mortality was high--71.4%, contrary to the group of electively operated patients in whom the mortality was 12.5% with a low postoperative morbidity and successful prevention of repeated bleedings.

Adult↗