[Methodology of preparing radial sections of the brain].
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Biomedical subjects
Publications and source records attributed to V D Chirkov.
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In the experiments on cats dumpfing of arterial and venous systems was carried out in order to study the functional state of CNS with blood supply under constant hydrostatic (mean dynamic) pressure. It was found that pulse oscillations of pressure in arterial and venous blood introduce marked distortions in ECoG. Blood supply under non-pulsatile pressure doesn't cause any considerable changes in the functional state of the cerebral cortex.
In acute experiments on unanaesthetized cats a study was made of the influence of shunting a region of the cortex with a metal plate on its electrical activity and impedance. Shunting of a region of strychninization reduces the amplitude of paroxysmal oscillations in the focus and in remote regions of the cortex, reduces their frequency and produces a considerable lowering of the impedance both in the regions of the cortex between the active electrodes and between active and indifferent electrodes. Impedance of the strychninized cortex is lower than the total resistance of the intact neocortex; this testifies to the rise of conductivity in the area of strychninization, which is similar to application of a shunting plate. The data obtained corroborate the substantial role of the bioelectrical field in the development of electroencephalographic paroxysmal manifestations.