PubMed Health⌕ Search

Biomedical subjects

V D Kartseva

Publications and source records attributed to V D Kartseva.

8 recordsLinked to original sources
PubMed1987

[Determination of the kanamycin B content of kanamycin preparations by column chromatography].

Kanamycin B content in kanamycin preparations was determined with column chromatography and PMR spectroscopy. It was shown that coincidence of the results obtained with both the procedures in analysis of the preparations subjected to additional recrystallization was satisfactory. With the use of nonrecrystallized preparations the admixtures interfered with the results in using the developed procedure.

Anion Exchange Resins↗
PubMed1987

[Azlocillin stability in solutions and the solid state].

Stability of azlocillin in aqueous solutions at pH 1.5-12.5 was studied at various temperatures. It was shown that degradation of the antibiotic proceeded as an irreversible first order reaction. Dependence of 1gk on the reverse temperature was described by the Arrhenius equation. The highest levels of azlocillin stability in solutions were observed at pH about 6.0. In solid state azlocillin was stable under the effect of the environmental factors. In the atmosphere of oxygen and carbon dioxide and on exposure to light the quality parameters of the antibiotic powder maintained at the control levels.

Azlocillin↗
PubMed1975

[Gentamicin stability and a method for its quantititive determination].

Stability of gentamycin in solutions at various pH levels was studied. It was shown that in acid media inactivation proceeded according to the equation of the 1st order reaction. Dependence of the inactivation rate constant on the temperature corresponded to Arrenium equation. A polarimetric procedure for determination of gentamycin providing the assay of the antibiotic levels at various purification stages biginning from the eluates after the ion-exchange columns is described. The results obtained with the above procedure were shown to correlate satisfactorily with those of the microbiological analysis.

Dose-Response Relationship, Drug↗
PubMed1975

[Rapid method for determining the stability of streptomycin sulfate powders].

A method applicable for beforehand determination of streptomycin sulfate powder stability by the colour of its solutions is described. It is shown that the results of such a determination satisfactorily coincided with the results of indirect determination of the solution colour after prolonged storage of the powders at room temperature.

Densitometry↗