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Biomedical subjects

V D Kosachev

Publications and source records attributed to V D Kosachev.

11 recordsLinked to original sources
PubMed1992

[Autonomic vascular disorders in neuropathies and the methods for their pathogenetic therapy].

Investigations were made to examine vegetovascular disorders in patients with inherited and acquired neuropathies (regional vegetative innervation, peripheral circulation and the thermal status of the limbs). Comprehensive, pathogenetically based treatment methods were developed. Using clinico-neurological, thermography, rheovasography and electrothermography research methods the following alterations were revealed in the autonomic areas of innervation of affected nerves: the signs of vegetovascular irritation; the signs of vegetovascular depression; a phenomenon of thermovision "amputation". Bearing in mind the diagnostic data, the patients were given differentiated pathogenetic therapy including physiotherapy and vegetotropic drugs.

Adolescent↗
PubMed1990

[Indicators of lipid peroxidation and erythrocyte membrane permeability in patients with myasthenia gravis].

Twenty-five patients suffering from myasthenia with no thymectomy were examined for lipid peroxidation (LPO) and erythrocytic membrane permeability. A study was also made of spontaneous and induced LPO, the level of diene conjugates and permeability of the erythrocytic membranes in mixtures of isotonic urea and sodium chloride solutions of varying volumetric concentrations. LPO activation which was coupled with an increase of erythrocytic membrane permeability was revealed. The data obtained point to the impairment of membrane apparatus function in patients with myasthenia and allow recommending the use of the membrane-stabilizing therapy.

Adolescent↗
PubMed1990

[Myasthenic crises].

The authors analyze the course of myasthenia complicated by the development of the myasthenic crisis, provide the data obtained over the recent 5 years by the clinic of nervous diseases of the Leningrad Institute of Advanced Medical Training, review the causes leading to the development of the myasthenic crisis, its clinical manifestations, discuss the problems of the diagnosis and treatment.

Adult↗
PubMed1990

[Lambert-Eaton myasthenic syndrome in bronchogenic carcinoma].

Six patients with Lambert-Eaton myasthenic syndrome were analyzed for the character of the initial symptoms, the clinical course and typical lesions on electrophysiological and x-ray studies. The given myasthenic syndrome often anticipates tumor symptoms and patients, as a rule, are seen for a long time by neuropathologists with a diagnosis of myasthenia. The data of ours indicate a real opportunity of the use of neurological and electromyographic criteria for goal-oriented search of bronchogenic carcinoma at the earlier stages of its development.

Action Potentials↗
PubMed1987

[Physical therapy of hereditary neuropathies].

In a series of 118 patients with the Charcot-Marie-Tooth neural amyotrophy the authors evaluated a comparative therapeutic efficacy of electrophoresis of benzohexamethonium and a new method of physiotherapy, namely, administration of ganglioblockers with the help of sinusoidal modulated currents. The results of the treatment were assessed from the time course of clinico-electrophysiologic parameters. The most marked positive course of the clinico-electrophysiological parameters was observed following electrophoresis of benzohexamethonium by sinusoid modulated current.

Adolescent↗
PubMed1986

[Pathogenesis and treatment of neural amyotrophy].

Examination of 214 patients with Charcot-Marie-Tooth muscular atrophy involved the use of thermography, rheovasography, electrothermometry, capillaroscopy, EEG and vegetative tests. The authors identified the most informative methods of early diagnosis and proposed a new method of therapy (electrophoresis with benzohexamethonium on the vegetative ganglia in combination with trental administration).

Adolescent↗
PubMed1984

[Early diagnosis and differentiation of Charcot-Marie neural atrophy].

On the basis of examination of 112 patients with Charcot-Marie-Tooth's neural amyotrophy, the differentiation between the classical form and atypical variants of the disease is carried out. The authors describe the diagnostic tests of the early diagnosis of the disease with the use of electromyographic, thermographic and histochemical methods of examination.

Adolescent↗