[Clinical forms of destructive pancreatitis and principles of its intensive therapy].
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Biomedical subjects
Publications and source records attributed to V D Malyshev.
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A study of some aspects of homeostasis and hemodynamics in surgical interventions for chronic coronary insufficiency helped reveal a difference in the nature of their changes depending upon the severity of the course and outcomes of the operation. With the latter running an uneventful course there is observed, as a rule, a moderate rise of the blood catecholamines level and their abundant passage with urine, which appears as a prognostically favourable sign. In operations complicated by the "syndrome of low cardiac ejection" terminating lethally there was definable, on the contrary, a high blood catecholamines content in conjunction with their reduced passage with urine. This was considered a prognostically adverse sign.
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Effects of 14 anesthetics, narcotic analgesics, benzodiazepines, and their combinations on the cardiac conduction system (CCS) were studied in 470 surgical patients of a general profile during operation and narcosis by transesophageal electrocardiostimulation. Interactions between components of total anesthesia can improve or suppress the intracardiac conduction. The authors classified the data on the effects of agents used for narcosis on the sinus node function and atrioventricular and anteretrograde conduction. The results will help an anesthesiologist in a differentiated approach to the choice of anesthetics for surgical patients with initially disordered CCS and heart rhythm.
Different anesthesias were used in 197 patients operated for supraventricular tachiarrhythmias through a transvenous access. Hypnoanalgesia based on preventive injection of a potent nonnarcotic antiinflammatory agent xefocame (lornoxicame), drip infusion of propofol (2-3 mg/kg/h), and bolus injection of dormicum under conditions of spontaneous respiration proved to be the best method.
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The anesthetic management course was analyzed in 224 patients who underwent nonvascular surgeries on the conductive heart system. Analgesic and anti-stress techniques, which do not affect the intracardial conductivity and ensure the successful outcome of surgery with spontaneous or auxiliary ALV, were designed on the basis of research. The above schemes were introduced in practice with their efficiency being confirmed. They are based on a balanced use of the new-generation non-steroid anti-inflammatory drugs, like Xephocam, bezodiazepines and fentanyl (when used at subnarcotic doses that do not affect the intracardial conductivity). The main analgesic component of lornoxycam was sufficient when used at a dose of 0.1 mg/kg and at a total dose of equal to or below 16 mg.
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