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Biomedical subjects

V D Ryndin

Publications and source records attributed to V D Ryndin.

At least 19 recordsLinked to original sources
PubMed1990

[Computerized tomography in the surgery of esophageal cancer].

Preoperative X-ray computerized tomography (CT) was performed in 60 patients with carcinoma of the esophagus at the All-Union Oncology Research Centre, USSR AMS in 1986-1989. The method is evaluated on the basis of comparison with the operative findings in determining the depth of invasion of the esophageal wall and adjoining structures by the tumor, metastatic involvement of the lymph nodes below the diaphragm, and metastases in the liver. Informativeness of X-ray CT proved to be highest in patients in whom the tumor had not spread beyond the esophageal wall. It was established that the method possesses high resolving possibilities in identification of enlarged lymph nodes in the abdominal cavity. Small metastases in the liver, measuring 0.5 to 2 cm in diameter, cannot be revealed by the method in some cases. The data gained by means of X-ray CT allows tactics of the surgical intervention to be determined and the late-term results to be predicted.

Esophageal Neoplasms↗
PubMed1990

[The combination of chronic lympholeukemia with other malignant neoplasms].

Altogether 23 patients examined for secondary tumors at the All-Union Cancer Research Center of the USSR AMS underwent a clinical analysis. The overwhelming majority of the patients (17) were subjected to surgical intervention. Of these, none of the patients developed any postoperative complications or showed progress of chronic lympholeukemia (CLL). No relationship was noted between cytostatic treatment of CLL and origin of second tumors. No correlation was revealed either between the duration of CLL treatment and the incidence of second tumors origin. The authors provide a brief review of the literature on the given problem. Give a summary of the statistics of the CLL incidence in other malignant neoplasms.

Aged↗
PubMed1990

[Garlock's operation in cancer of the esophagus].

Experience in 88 Garlock-type operations carried out in carcinoma of the esophagus allows a certain opinion to be formed on the advantages and shortcomings of this surgical intervention. In esophageal carcinoma with its proximal boundary within the range of the retropericardial segment of the esophagus, a left abdominothoracic approach (Garlock's operation) is adequate in resection of the esophagus in conformity with the oncological principles and allows the formation of the esophagogastric anastomosis at the level of the arch of the aorta without particular technical difficulties. Reduction of the time needed for the operation, determination of the resectability of the esophageal tumor before mobilization of the stomach are obvious advantages of the abdominothoracic approach.

Carcinoma, Squamous Cell↗
PubMed1990

[Surgical and combined treatment of esophageal cancer].

The authors analyse 37-year experience in the treatment of patients with esophageal carcinoma by various methods at the All-Union Cancer Research Center. The immediate and long-term results of radiotherapy and surgical and combined treatment of 1,850 patients are shown. Bearing in mind the considerable extension of the neoplastic process by the time of the operation, the authors substantiate the expediency of one-stage operations with the formation of intrapleural esophagogastric anastomoses. The mortality in the recent years after 218 Lewis' operations and 36 Herlock's operations was 9.0%. After analysing experience in combined treatment, the authors failed to reveal any particular advantages over solely surgical treatment, but in view of the lack of other alternatives for improving the results of management of esophageal carcinoma to-date, they believe it expedient to continue study and improve various combinations of preoperative radio-(chemoradio)therapy and operation in large research centres.

Antineoplastic Agents↗
PubMed1986

[Radionuclide determination of the extent of the tumor process in patients with esophageal cancer].

Scintigraphy with 67Ga-citrate and 111In-bleomycin was conducted in 32 esophageal cancer patients, 4 patients with benign esophageal tumors and in 3 patients with scarry-ulcerous esophagitis. A raised accumulation of the radiopharmaceutical (RP) in the esophagus, in 4 cases in the retroperitoneal paraaortic lymph nodes in which a metastatic image was confirmed at computed tomography and diagnostic laparotomy, was observed in all cancer patients. No regularities in the intensity of the accumulation of both radiopharmaceuticals in the esophageal tumor with relation to its histological structure were detected. The advantage of the above radiopharmaceuticals is a possibility to use them for the detection of tumor dissemination and distant metastases in esophageal cancer.

Adult↗