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V Dimitrova

Publications and source records attributed to V Dimitrova.

At least 73 records · Page 4Linked to original sources

[Gastric polyposis in surgical practice. Apropos 12 cases].

Personal experience is recorded in the surgical treatment of 12 patients with gastric polyposis at the Department of Propaedeutics of Surgical Diseases of the Research Institute of Surgery, for a period of 10 years (1981-1990). They accounted for 75 per cent of the benign neoplasms of the stomach and 4.08 per cent of all gastric tumors. The results of operative treatment, both in patients treated by gastric resection according to Billroth I technique (58.3 per cent) and in patients who were treated only by removing the polyps (41.7% per cent) were considered good within a follow up period of 1 to 5 years after the intervention. Proceeding from modern achievements and reports in the literature, the authors place accent on some important current aspects of treatment and observation on gastric polyps, their correlation with a number of hyperplastic diseases and malignant neoplasms of the stomach and colon.

Adult↗

[Duodenal carcinomas. Apropos 3 cases].

Three personal cases of duodenal cancer treated at the Department of Propaedeutics of Surgical Diseases of the Research Institute of Surgery in Sofia for the period 1981-May 1990 are reported. They accounted for 0.27 per cent of the patients with cancer of the gastrointestinal tract and 0.39 per cent of those with intestinal cancer. Two patients has adenocarcinoma and 1 leiomyosarcoma. Data available in the literature are adduced and analysis made of the symptoms, operative mortality and postoperative survival. The need of early diagnosis of duodenal cancer and the methods for this are pointed out. The major importance of the prophylaxis and competent approach to obligate and non-obligate precancerous duodenal diseases is emphasized.

Adenocarcinoma↗

[Semilunar ganglionectomy and the pain syndrome of pancreatic origin].

Personal seven-year experience (1984-1990) with the application of semilunar ganglionectomy in 25 patients with basic indication for pancreatic cancer (20 patients) and chronic pancreatitis (5 patients). Attention is called on the basic points in the original technique of Legé and the authors' own modifications of this technique. The indications and contraindications for performing the operative intervention were determined. The early postoperative results in 84 per cent of the cases (regardless of the type of diseases) were excellent as regards the pain; in the remote postoperative period the results were poor. The causes of the poor results of semilunar ganglionectomy are analyzed. The most common cause was the generalization of the malignant processes in the pancreas and the faulty performance of the intervention. The major importance of this operation in the treatment of chronic indurative pancreatitis with narrow pancreatic canals and its value when combined with other derivation methods in the operative treatment of pancreatic surgical diseases are pointed out.

Chronic Disease↗

[Our experience with the use of the new Bulgarian intrauterine contraceptive device, the Venus Cu 300 (preliminary report)].

A team of the family planning centre at the Research Institute of Obstetrics and Gynecology carried out a trial on a new Bulgarian intrauterine contraceptive device (ICD), produced by the firm Venus in the town of Varna: Venus Cu 300. This is a T-shaped device with horizontal arm of 30 mm, vertical arm of 34 mm, a copper thread with an area of 300 mm2 and two control threads. It is produced from PVC. Purity of copper is over 99.9% in the copper thread. The construction of Venus Cu 300 has the positive properties of other intrauterine contraceptive devices, used in our country during the last 15 years. 87 women have been followed in 320 cycles for a period of 6 months. A larger part of them are parous, mainly with one or two children. Venus Cu 300 has been used in seven nulliparas, presenting risk for frequent abortions. Three Venus Cu 300 have been placed immediately after abortion. No pregnancy occurs, which is explained by the careful choice of the patients. Extraction of ICD has been made only in one case due to medical causes: bleeding and pain. More abundant menstruation after ICD has been found in 11.5% of women, but there has been no need to extract ICD. Inferences are made that Venus Cu 300 is in every way equal to the known models of ICD, that the trial should include a larger group of women to accumulate data in dynamics, in order to improve Venus Cu 300 eventually.

Adult↗

[Mesangial C3-glomerulonephritis].

12 patients with mesangial C3-glomerulonephritis, 7 women and 5 men, aged 16-42, mean age 29.7 years, were followed up for 1-18 years, mean time 5.7 years. The disease was manifested most often by macroscopic hematuria or low degree proteinuria. Single patients had arterial hypertension. In only one patient there was a nephrotic syndrome. For the period of observation, impairment of the renal function was found in none of the patients.

Adolescent↗

[Cholelithiasis, cholecystectomy and colorectal cancer--a retrospective analysis].

The authors analyzed a series of 421 patients with colorectal cancer after preliminary review of the current literature and the modern theories of the origin of the disease. The patients have been treated at the Department of Propedeutics of Surgical Diseases, Research Institute of Surgery, for the period 1984-1990, and special accent was placed on the study of the relation of colorectal cancer to cholelithiasis and cholecystectomy. It was shown that 1.19 per cent of all patients had been cholecystectomized at mean 10.6 years back and 6.65 per cent had pre-existing or accompanying biliary calculosis with mean duration of symptoms 16.4 years. A major relationship was found between morbidity from colorectal cancer, on the one hand, and patient sex and biliary calculosis, on the other. Eighty nine per cent of the patients with colorectal cancer and with biliary calculosis treated by cholecystectomy were women and 20.3 per cent of the women with colorectal cancer had biliary calculosis and had been cholecystectomized. Attention is focused on the current practical requirements of the prophylaxis of colorectal cancer--adequate attitude to biliary calculosis, feeding habits, specifying cases at risk and their observation.

Age Factors↗

[Malignant non-Hodgkin's lymphomas in abdominal surgery: apropos 3 cases of Burkitt's lymphoma].

On the occasion of three observations of the extremely rare and malignant Burkitt's lymphoma, the authors record their 7-year experience in the operative treatment of 22 patients with non-Hodgkin's malignant lymphomas. Proceeding also from data available in the current literature, the most frequently encountered syndrome-complex is presented, the knowledge of which is of major importance for the early diagnosis, resp. for the results of combined treatment. The possibilities of the operative treatment are evaluated. In the authors' series it was radical in 31.8 per cent of the cases with 13.6 per cent early postoperative lethal outcome and 5.2 months average postoperative survival rate. Proceeding for the rarity of the disease in everyday surgical practice and that it is poorly known, but has become a nosologic entity of increasing interest, the authors have devoted the first part of their article to a discussion on the basic characteristics of non-Hodgkin's malignant lymphomas and the modern achievements of their treatment.

Abdominal Neoplasms↗

[3 cases of acute postoperative pancreatitis].

After a brief review of the literature the authors present three cases of acute postoperative pancreatitis in patient operated for different reasons with lethal outcome. In one patient the complication developed after duodeno-hemipancreatectomy and is the only patient with such complication (2 per cent) of 50 patients in whom radical operation was performed for cancer of the pancreas over the period Jan. 1983-May 1990. The current aspects of the etiology, treatment and above all of the prophylaxis of acute postoperative pancreatitis, which is a very serious postoperative complication with very high case fatality rate (up to 77 per cent, according to data in the literature) are discussed.

Acute Disease↗

[Our experience with the surgical treatment of acute gynecological diseases].

Experience is recorded in the treatment of acute gynecological diseases based on a series of 61 patients operated in the Clinic of Propedeutics of Surgical Diseases at the Research Institute of Surgery in Sofia for the period Jan. 1983-April 1990. They comprise 6.08 per cent of all emergency cases. The most common gynecological pathology was, as follows: 59 per cent ovarian cysts, 11.5 per cent adnexitis, 26.2 per cent adnexitis + pelvioperitonitis, 6.6 per cent extrauterine pregnancy, etc. The early postoperative results were very good--zero case fatality rate, absence of serious complications, 6.6 per cet suppurations. Taking into account also the very good remote results, the authors point to the trivial appraisal of the surgical activity and the need of thorough evaluation of the patient's fertility, all the more that 78.7 per cent of the women were younger than 39. In the light of the current trends in gynecological practice, the authors specify the indications and contraindications for surgical interventions in these diseases.

Acute Disease↗

[The place of the screening method in the early discovery and treatment of cryptorchism].

According to modern concepts, only early operative treatment of cryptorchidism may guarantee good results. This has been proven by the results obtained by the authors, who for five years have on mass prophylactic examination (1984-1988) searched for cryptorchidism in children attending kindergartens in the town of Tolbukhin. In this way the authors succeeded in realising highest operative activity in the age from 3 to 4 years.

Age Factors↗

[The effect of treatment on the survival rate in chronic glomerulonephritis].

The survival rate of 68 patients with immunoglobulin A glomerulonephritis (IgA GN), 29 patients with membranous glomerulonephritis (MGN), 13 patients with membranous-proliferative glomerulonephritis (MPGN) and 40 patients with lupus glomerulonephritis (LGN) was assessed using the life registration tables. The patients with IgA GN were treated symptomatically, and the remaining patients were treated with a combination of corticosteroids, immunosuppressors and anticoagulants. At the 10th year from the onset of the disease the survival rate was as follows: for the patients with IgA GN--88%, with MGN--94.9%, with LGN--81.0% and with MPGN--61.6%. The comparison with the survival rate established for the respective types of glomerulonephritis without treatment or the presence of mixed groups of treated and nontreated patients shows that the combined pathogenetic treatment improves the prognosis of MGN, LGN and of a number of patients with MPGN and it nears that of the comparatively more benign IgA GN.

Age Factors↗

[Transduodenal papillosphincteroplasty in the treatment of benign diseases of the terminal choledochus and papilla Vateri].

The modern state of the problem and the indications and contraindications for performing transduodenal papillosphincteroplasty are discussed. Personal experience is recorded with 67 transduodenal papillosphincteroplasties, performed for the period 1983-1989, against the background of 1091 operations on the hepatobiliary system, 171 of them on the extrahepatic bile ducts, performed during the same period. Proceeding from their own experience and from available data in the literature, the authors analyse and evaluate the surgical and nonsurgical methods of treatment of benign diseases of the terminal common bile duct and the duodenal papilla, manifested by stenotic lesions. The most important indications and contraindications for applying the different therapeutic methods are adduced. Remarks are made on the technique, which is of major practical importance and the respective conclusion is substantiated.

Adult↗