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V Domínguez Rojas

Publications and source records attributed to V Domínguez Rojas.

At least 19 recordsLinked to original sources
PubMed2004

[Influence of the diet on the development of colorectal cancer in a population of Madrid].

OBJECTIVE: Although the genetic component in colorectal carcinoma (CRC) is well established, some environmental factors, mainly dietary, can favor its development. The objective of this study is to evaluate the relationship between daily consumption of specific food groups and development of CRC. METHODS: We carried out a case-control study in an area of Madrid; 196 patients with diagnosis of CRC with confirmed histology and registered to May 1998 in the Community of Madrid tumor register were included, and they were compared with 196 controls matched by age, sex, and geographical area. All of them filled out a questionnaire with information on diet, substance abuse, physical activity, drugs, and family history of CRC. RESULTS: The logistic regression analysis showed a weakly positive association with meat (OR: 1.02; CI: 1.01-1.04), viscera (OR: 1.12; CI: 1.02-1.23), and sausage (OR: 1.07; CI: 1.03-1.1) consumption, and a modest inverse association with consumption of yogurt (OR: 0.97; CI: 0.95-0.98), tomato (OR: 0.99; CI: 0.98-0.99), strawberries and cherries (OR: 0.97; CI: 0.95-0.99), oranges, grapefruits, and natural fruit juices (OR: 0.99; CI: 0.98-1). CONCLUSIONS: These results are an additional empirical evidence that must be confirmed through prospective studies.

Case-Control Studies↗
PubMed2000

[Incidence of dental caries in a child population from Mostoles: evaluation of a preventive program after 2 years].

OBJECTIVE: To know the efficacy and effectivity od dental health program after 2 years. DESIGN: The study of prospective cohorts not aleatorized. POPULATION AND METHODS: The exposed cohort is composed of 583 school children, 296 girls and 287 boys, the non-exposed cohort is composed of 261 school children, 132 girls and 129 boys. We carried out and odontological exploration following the criteria of the WHO the preventive measures we carried out are health education, weekly mouthrinse of NaFl at 0.2%, occlusive sealant in the first permanent molar and external application fluorine gel. We measured and compared the different indexes of tooth decay and sociodemographic variables between both cohorts, the statistic meaning has been determined through the U est of Mann Whitney. RESULTS: We have found statistically significant differences between both cohorts in the indexes of decay in the exposed cohorts. The indexes of decay in the exposed cohort being DMFT: 0.31; DMFM (first permanent molar): 0.31; DMFS: 0.4. And in the non-exposed cohort DMFT: 0.81; DMFM: 0.81; DMFS; 1.09. Existing an epidemiological association between the preventive program and the prevention of dental decay with a relative risk of 0.24 (95% CI, 0.17-0.33) and the prevention fraction of 76.3% (95% CI, 67-83). CONCLUSIONS: The preventive program after two years elapsed is effective and has a clear protector effect.

Child↗
PubMed1999

Familial aggregation of cardiovascular disease risk factors: the Cuenca Study.

OBJECTIVE: The familial aggregation of lipid levels, blood pressure, and body mass index (BMI) was studied in schoolchildren in Cuenca, Spain. METHODS: A cross-sectional observation study was made of 307 schoolchildren of both sexes, age range 9-12 years, from three schools in Cuenca, Spain, and of 346 parents. Social and demographic variables, weight, height, body mass index, systolic blood pressure, diastolic blood pressure, and fasting plasma concentrations of total cholesterol, LDL-cholesterol, HDL-cholesterol, and triglycerides were evaluated. RESULTS: The Spearman coefficients of correlation for total cholesterol, LDL-cholesterol, and BMI for parents and daughters were 0.34-0.42 (P < 0.01). These coefficients of correlation for parents and sons were lower (P > 0.05). The coefficient of correlation for blood pressure in parents and sons was low (P < 0.05). None of the variables showed any coefficient of correlation between spouses. The sexual differences in the correlations between the levels of the different variables were confirmed by multiple regression analysis. Total cholesterol and LDL-cholesterol levels and BMI accounted for larger percentages of variability in these parameters in daughters than in sons. The paternofilial aggregation of HDL-cholesterol and triglyceride levels was weak. The only variable that accounted for a significant variability in blood pressure (systolic and diastolic) was weight in children of both sexes. CONCLUSIONS: The familial aggregation of lipid levels and body mass index showed sex differences. The paternofilial aggregation of blood pressure was weak. There was no relation between spouses.

Adult↗
PubMed1999

[Seroprevalence of antibodies against measles, rubella, mumps and varicella among school children in Madrid].

OBJECTIVE: The aim of this study was to assess the seroprevalence of antibodies against MMR and varicella in a population of children between 6 and 7 years of age vaccinated against measles, mumps and rubella at 15 months of age. PATIENTS AND METHODS: This cross-sectional study was carried out in a group of healthy children (6-7 years of age) of the Autonomous Community of Madrid, Spain. Vaccination against MMR at 15 months of age was documented for all children included in the study. Blood samples were drawn from all participants and sera were stored at -20C until they were tested at the end of the study. Measles, mumps, rubella and varicella antibody levels were measured by means of the enzyme linked immunosorbent assay (ELISA) method (IgG Genzyme Virotech GmbH). Positive values were defined as optical density values of > or = 0.20 for measles, > or = 0.30 for mumps, > or = 0.40 for rubella and > or = 0.36 for varicella. Prevalence (and the corresponding 95% confidence limits) assessed by the presence of anti-measles, anti-mumps, anti-rubella and anti-VZV antibodies on the study population were calculated. The Chi-squared test was used to evaluate differences in prevalence between sexes. The Chi-squared test was used to evaluate differences in prevalence between the sexes. RESULTS: A total of 174 children were recruited between October and November 1997. The mean age (SD) and male/female ratio were 6.4 (0.5) years and 0.8 (45.6%/54.5%), respectively. Prevalence of antibodies against measles, rubella, mumps and varicella were 92% (88-96%), 95% (92-98%), 81% (76-86%) and 85% (90-90%), respectively. There were no significant differences between the sexes in relationship to the prevalence of measles, mumps, rubella or varicella antibodies. CONCLUSIONS: Approximately 20% of these 6 to 7 year old children vaccinated at 15 months of age were unprotected against the mumps. Eight percent and 5% were sero-negative for measles and rubella, respectively. Administration of the second dose of MMR vaccine at 4 to 6 years of age instead of at 11 years would contribute to avoid the accumulation of non-immune children. Eighty-five percent of the study population was sero-positive for VZV. These data suggest that, in Spain, VZV infections commonly affect children younger than 5 years of age.

Antibodies, Viral↗
PubMed1999

[Functional deterioration secondary to hospitalization for an acute disease in the elderly. An analysis of its incidence and the associated risk factors].

OBJECTIVE: To determine the incidence of functional impairment at hospital admission and after hospital discharge, and to identify those factors that could be predictors of such impairment in a cohort of elderly people with high level of independence in the basic activities of daily living (BADL). DESIGN: Epidemiologic, longitudinal and prospective study. SETTING: Acute unit in a geriatric department. SUBJECTS: The follow-up population was made up by 150 subjects older than 65 years, admitted on account of acute medical conditions from December, 15th, 1995, to December, 15th, 1996, who were independent for walking and independent or with slight dependence for BADL. STUDY PARAMETERS: All patients were evaluated at 48 hours after admission and one month after discharge by means of a protocol including sociodemographic, clinical, attending, functional and mental parameters. RESULTS: The incidence of functional impairment at hospital admission was 70.66%; such impairment persisted one month after discharge in 29.3% of subjects. The most involved activities related to motility. In the analysis of crude data, the following parameters showed association with functional impairment risk one month after discharge: female sex (OR: 2.5), sensorial organ pathology (OR: 2.6), hospital stay longer than 15 days (OR: 7.2), and Lawton Index score (3.8 +/- 2.6 in impaired patients vs. 4.9 +/- 2 in non-impaired patients; p < 0.01). Barthel Index score at admission lower than 60 (OR: 9.5), Cognitive Miniexam score lower than 28 (OR: 4.1), Informant Test score higher than 84 (OR: 2.5) and Geriatric Depression Scale score 9 (OR: 3.1). In the logistic regression model, the following parameters remained as predictors of impairment: sex (OR: 3.3), days of hospital stay (OR: 2.3) and Barthel Index score at admission (OR: 6.1) and Cognitive Miniexam score (OR: 2.7). CONCLUSIONS: For our population, sex, hospital stay days, functional impairment in Barthel Index at admission and Cognitive Miniexam score parameters seem to behave as independent variables that can predict functional impairment risk for BADL one month after discharge. These parameters could be useful to select groups of elderly people with impairment risk, who could benefit from specialized interventions leading to prevent/decrease functional impairment secondary to acute disease and hospitalization.

Activities of Daily Living↗
PubMed1998

[Familial aggregation of arterial pressure figures and weight indices: study in Cuenca].

BACKGROUND: The aim of this study was to assess the familial aggregation of blood pressure and body mass index levels in schoolchildren of Cuenca city, Spain. SUBJECTS AND METHODS: A cross sectional study was made including 307 both sexes schoolchildren 9-12 years old recruited in three schools of Cuenca city, and 346 of their parents. There were determined sociodemographics variables, weight, height, body mass index, SBP, DBP and fasting plasma total cholesterol, cLDL, cHDL and triglyceride concentrations. RESULTS: Parents-children correlation coefficients in blood pressure levels ranged between -0.1 and 0.2. Parents-daughters correlations were stronger than parents-sons in ponderal indexes. The relationship of ponderal indexes and blood pressure between spouses was weak, with correlation coefficients between 0.08 y 0.1. By stepwise multiple regression analysis it was found that the only variable that explained a significant percentage of blood pressure variability (both systolic and diastolic) was the weight of the schoolchildren in both sexes. Parents body mass index explained more than 32% of body mass index daughter's variability. In sons any variable explained a significant percentage of variability. CONCLUSIONS: The parents-children aggregation of blood pressure is weak. Parents-children aggregation of ponderal indexes is stronger, though there are considerable sex-differences. Spouses relationship, though positive, is weak in all variables.

Blood Pressure↗
PubMed1997

[Familial aggregation of lipid and lipoprotein levels: the Cuenca study].

BACKGROUND: The aim of this study was to assess the familial aggregation of lipid levels in schoolchildren of Cuenca city, Spain. SUBJECTS AND METHODS: A cross sectional study was made including 307 both sexes schoolchildren 9-12 years old recruited in three schools of Cuenca city, and 346 of their parents. Sociodemographics variables, weight, height, body mass index, systolic blood pressure, diastolic blood pressure and fasting plasma total cholesterol, LDL-C, HDL-C and triglyceride concentrations were determined. RESULTS: Father-daughter and mother-daughter Spearman rank correlations coefficients in total cholesterol and LDL-C levels showed values ranging from 0.34 to 0.42 (p < 0.01). Correlation coefficients between both parents and between parents and sons were not significant. By stepwise multiple regression analysis it was found that parents' total cholesterol levels explained almost 30% of cholesterol variability in daughters and 10% in sons. This proportion was about 25% for LDL-C in daughters and was not significant in sons. Parent-children aggregation of HLD-C and triglycerides was weak. CONCLUSIONS: Parent-daughter aggregation of lipid and lipoprotein levels was stronger than parent-son, which has been evidenced mainly in total cholesterol and LDL-C. It has been found no evidence of relation between parents.

Adult↗
PubMed1991

[Dental caries: age, income level and dental care].

We have studied a population of 527 school children between 6 and 17 years old, having as main characteristic to have free odontological care. The prevalence of caries found was 40.4%. The age appears as a risk factor. However, we have not found any influence in the social status. The odontological care is considered essential in the decrease of prevalence of dental caries.

Adolescent↗
PubMed1990

[Dental care for 6 to 15-year old children].

It has been realized a descriptive study about odontological assistance in 883 schoolchildren, they are from Madrid, attending age, sex and social status. Equally we analyze the variable dental caries in relationship with social class and odontological assistance.

Adolescent↗
PubMed1990

[Epidemiological study and development of dental caries in Madrid students].

It has been done an epidemiologic study about dental caries prevalence in a school population in Madrid. We have studied 3,608 schoolchildren. Total caries prevalence was 53.4%, according other authors. Caries is more frequent between ten years children. We also observed low prevalence in the third year of the study.

Age Factors↗
PubMed1990

[An epidemiological study of tuberculous infection].

We have the stage (or condition) of the tuberculous infection in a groups of 1,450 Schoolchildren aged between 6 and 13 years living in Madrid during the school-year 1988/89. For this we used the PPD-RT 23 tuberculin applying 2UT and considering as positive those reactions which were equal or greater 10mm. The prevalence of the tuberculous infection was 1.47% for children aged 6 years and acquire 4.3% for those aged 13 years with greater risk of 3.02 to acquire the infection in the children aged of thirteen in opposition with those of six years. There are no significant statistical significant statistical differences between boys and girls, nor between private and public colleges. We also found that the annual increment of the infection for the vaccinated-children was of 0.14%, while in no vaccinated it was of 0.64%, being of 0.41% for the whole group. The finally we emphasized the existence of a clear increment of the tuberculous infection related to age-group, being the risk of infection greater in no-vaccinated children aged of 13 and from the other part the necessity to amplify the time duration of this type of studies in order to calculate the RAI in Madrid.

Adolescent↗
PubMed1990

[Caries prevalence of a school population].

We have made a cross-sectional study about dental caries in 883 children between 6 and 15 years old, belonging to 3 public schools representing the municipal district of Tetuan (Madrid). The studied variables, that were related with presence/absence of caries were: age, sex, school, social class, number of meals per day, tooth brushing and use of fluor. We have also established the indexes DMFT, dmft, DMFM, together with the affection percentage of each tooth and its graphic representation.

Adolescent↗
PubMed1988

[Socioeconomic status and growth in school children].

We admit that somatic growth depends on genetic and nutritional factors, and that the latter are related to social and economic status of the population. To test the hypothesis that social and economic status is associated with growth, we have carried out in Madrid a cross-sectional study among 2,983 school children aged 6 to 14 years old. It shows a consistent positive association in all age brackets between socio-economic status and growth among school girls, suggesting a need for nutrition educational programs in this population subgroup.

Adolescent↗