[Anatomo-clinical conference. Hôpital de la Pitié-Salpêtrière. Case n. 1--1988. Lymph nodes, spleen and hypoglycemia].
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Biomedical subjects
Publications and source records attributed to V Duchatelle.
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14 cases of mammary hamartomas are reported. The WHO describes the mammary hamartoma, as a pseudo-tumor made of ducts and lobules, with fibrosis or adipose connective tissue. The mammogram consists in a well circumscribed tumor generally surrounded by a defined zone of less attenuation. Surgically, the hamartoma can usually be enucleated. Microscopy reveals lobules always but inconstant adipose tissue. Confrontation between gross and histologic features are necessary for the diagnosis. The embryologic development of the mammary gland could help to explain the origin of such a lesion, malformative rather than tumorous.
A 37-year-old black West Indian woman with sarcoidosis developed obstructive jaundice due to stenosis involving the entire length of the common hepatic bile duct associated with stenosis of the cystic duct. Neither gallstones nor extrahepatic biliary tract lymph node involvement were found. Stenosis was ascribed to biliary involvement of sarcoidosis because of the presence of noncaseating granulomas in the cystic duct and the gallbladder neck. There was no hepatic involvement. Cholecystectomy and left hepaticojejunostomy were performed. Postoperative recovery was unremarkable. Jaundice disappeared and liver tests returned to normal values. This case report underlines the importance of verifying the patency of the extrahepatic biliary tract before severe cholestasis can be ascribed to intrahepatic involvement of sarcoidosis.
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