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V Dvonch

Publications and source records attributed to V Dvonch.

8 recordsLinked to original sources

Ethical dilemmas. The new is old.

There are no predictable external cues to ethical dilemmas, therefore, physicians must develop internal sensitivity to these issues. Because there is only a finite number of ethical problems, these recur with predictable frequency. The current essay reviews three books from the literature that present ethical difficulties that were unrecognized until the consequences were obvious. By considering these, and their parallels today, present physicians may avoid the ethical mistakes of their predecessors.

Authorship↗

Platelet-derived growth factor AA homodimer is the predominant isoform in human platelets and acute human wound fluid.

Platelet-derived growth factor (PDGF) is a dimeric protein composed of A- and B-chains (AA, AB, and BB). PDGF purified from human platelets has been shown to be composed primarily of the AB heterodimer. Immunoblots of total platelet extracts, cell-bound PDGF from the platelet extracts, and acute human wound fluid with PDGF A- and B-chain-specific antisera all demonstrate that the PDGF A-chain is the predominant peptide. Chemotactic and immunochemical assays of chromatographic fractions during PDGF isolation support these observations and demonstrate that PDGF AA can be separated from PDGF AB and BB by ion exchange chromatography. These studies indicate that the AA isoform constitutes the major PDGF dimer contained in human platelets and is the major form present at sites of injury during the acute phase of the wound repair response.

Amino Acid Sequence↗

Limping toddlers.

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Bone Diseases↗

Dermatomal somatosensory evoked potentials: their use in lumbar radiculopathy.

The accurate diagnosis of lumbar radiculopathy secondary to intervertebral disc herniation or spinal stenosis remains a significant problem. Studies have stressed that misdiagnosis of root entrapment significantly contributes to the incidence of failed back syndrome. In an attempt to aid the proper selection of surgical candidates, dermatomal somatosensory evoked potentials ( DSSEP ) have been used in conjunction with standard diagnostic techniques to evaluate our patients. The advantage of this technique lies in the root specificity. The authors studied the DSSEP using two methods. In Method 1, using myelograms as the standard, the accuracy was 85.7%. In Method II, using surgical outcome as the standard, the accuracy was 87.5%. As a result, the authors have found the noninvasive, relatively inexpensive DSSEP to be a useful adjunct in the selection of patients undergoing lumbar spine surgery.

Afferent Pathways↗