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Biomedical subjects

V E Egwuatu

Publications and source records attributed to V E Egwuatu.

At least 19 recordsLinked to original sources
PubMed1990

Vaginal delivery in Nigerian women after a previous cesarean section.

A total of 154 consecutive Nigerian women at term pregnancy who had undergone one previous cesarean delivery were prospectively studied during the year March 1987 to February 1988. A repeat elective cesarean section was performed in 52 (33.8%) patients. Vaginal delivery was achieved in 73 (71.6%) of the 102 subjects who were allowed into labor, and in over 90% of the comparison group. High vaginal delivery rates occurred among the women within the selection criteria irrespective of the indication for the previous cesarean section. A repeat emergency cesarean section was performed in 29 (24.5%) women. Rupture of the uterine scar occurred in 5 (4.9%) instances with the loss of 2 babies; there was no maternal loss. Excluding the high incidence of fetal asphyxia and uterine rupture which occurred among women in the study group, maternal morbidity and perinatal mortality and morbidity were similar to those of the comparison group. There was a statistically significant difference between the study and comparison group. There was a statistically significant difference between the study and comparison groups with regard to the mode of delivery. Among the study group, a significant correlation existed between the vaginal delivery rate of the patients and the indication for the primary cesarean section. There was however, no significant difference between the mean parities of the women who were delivered by cesarean section and those who delivered vaginally. Similarly, no significant difference existed in the mean birthweights of the babies delivered vaginally and those who were delivered abdominally during labor.(ABSTRACT TRUNCATED AT 250 WORDS)

Birth Weight↗
PubMed1989

Observations on molar pregnancy in Enugu, Nigeria.

Forty-one molar pregnancies seen at the University Teaching Hospital Enugu, Nigeria during the 10-year period 1976-1985 are analyzed. The incidence of hydatidiform mole was 0.82 per 1000 pregnancies. The incidence of molar pregnancy was lowest among teenage women and increased markedly with advancing age over 35 years. Hyperemesis gravidarum, a relatively uncommon finding in Nigerian women during normal pregnancy was a prominent feature of molar pregnancy in the women. The incidence of postmolar gestational trophoblastic disease was 17%; choriocarcinoma occurred in 7% of the subjects. Molar pregnancy and postmolar malignant trophoblastic disease occurred much less frequently among the Igbo women of Enugu than the Yorubas of western Nigeria. Earlier and better recognition and treatment of hydatidiform mole will probably result in a decrease in the high rate of complications found during this study.

Adolescent↗
PubMed1989

Non-Hodgkin's lymphoma of the uterus in a child.

A unique case of a 14-year-old girl with malignant lymphocytic lymphoma of the uterus clinically misdiagnosed as sarcoma botyroides is presented. Total abdominal hysterectomy was performed followed by limited chemotherapy. The patient is asymptomatic and without clinical evidence of tumor 38 months after the onset of symptoms.

Adolescent↗
PubMed1986

Childbearing among the Igbos of Nigeria.

Traditional Obstetric care among women of the Igbo tribe in Nigeria is described. The role of traditional birth attendants, antenatal care, management of delivery complications, postnatal care and traditional community practices surrounding birth are discussed.

Delivery, Obstetric↗
PubMed1986

Complications of cervical cerclage in Igbo women.

Igbo women inhabit one of the most densely populated regions of Africa. This study suggests that cervical incompetence in Igbo women is prevalent among the literate and higher socioeconomic group, that it occurs at an earlier age when compared with published series, possibly reflecting earlier marriage and childbearing, and that the damage occurs mostly during the first or second delivery.

Adult↗
PubMed1986

Plasma concentration of urate, urea and creatinine in Nigerian primigravidae with pre-eclampsia.

Single estimations of plasma urea, uric acid and creatinine were made in late pregnancy in 34 Nigerian primigravidae with mild/moderate or severe pregnancy-induced hypertension, and in 34 matched primigravidae with uncomplicated pregnancy. The differences in mean plasma concentrations of uric acid and creatinine between the pre-eclamptic patients and the normotensive controls were statistically significant, while that in mean urea levels was not. Patients with severe (proteinuric) pre-eclampsia showed significantly higher plasma urea and urate concentrations than women with mild/moderate (aproteinuric) disease, but the difference in mean plasma creatinine values between the two groups was not significant. In the pre-eclamptic group, changes in the plasma concentrations of the substances were more prominently correlated with the degree of proteinuria than the level of hypertension. Of the three substances examined, changes in the blood urate concentrations were the most pronounced. The slight fall in the mean blood urea level in patients with mild/moderate pre-eclampsia followed by an abrupt and significant rise as pre-eclampsia became severe might reflect variations in fluid distribution rather than raised urea production or impaired excretion. High blood uric acid and urea levels in women with proteinuric pre-eclampsia are associated with increased fetal risk and should be an indication for closer monitoring of the function of the feto-placental unit.

Adolescent↗
PubMed1984

The sex ratio of Igbo births.

The study determined that the sex ratio of live-born infants in the Igbo-occupied area of Nigeria is about 1.04. This figure, although similar to the 1.03 reported for Zaire and for the black populations of the US and the Caribbean, is lower than the 1.05 to 1.07 accepted for most European populations, the 1.06 recorded for the Yorubas of western Nigeria, and the 1.07 reported for the Hausa people of one northern Nigerian province. Values ranging from 1.12 to 1.14 have been reported for Africans of Uganda and Cameroun. All these figures are lower than the 1.15 recorded for the Far Eastern peoples and support the widely held impression that the sex ratio at birth is influenced by, among other factors, geographical and genetic distribution. Results of the study of Igbo births also showed that the sex ratio within a homogeneous population varies with place of confinement, from a high in hospitals to a low in community health centers.

Adolescent↗
PubMed1983

Plasma urate, urea and creatinine levels during pregnancy and after the puerperium in normal primigravid Nigerians.

Plasma concentrations of urea, uric acid and creatinine were measured in 55 normal primigravid Nigerians during pregnancy and 6 weeks after delivery. Plasma urate concentrations were lowest in early pregnancy and increased with advancing gestation, achieving the highest values in the postnatal period. These findings are similar to those reported for European women. Plasma urea rose during the second trimester, fell in the third to almost first trimester levels and rose again in the postnatal period. Plasma creatinine generally followed the same pattern as urea. It is suggested that these changes are a reflection of fluid distribution rather than a change in urea and creatinine production. An improved nutritional status may explain the urea values which are higher than previously reported in African women.

Adolescent↗
PubMed1982

Xylose absorption and oral glucose tolerance test in pregnant and non-pregnant Nigerian women.

Xylose absorption and oral glucose tolerance tests (OGTT) were carried out on 16 healthy Nigerian women at various stages of their first pregnancy, and on 18 normal female medical students of comparable age and build. In all cases the OGTT showed the flat-like curve pattern characteristic of most Nigerians. In both the pregnant and non-pregnant state, the xylose excretion was within normal limits. It is concluded that the unusual 'flat' OGTT curve in Nigerians is not due to failure of absorption. It is suggested that the slight differences in the OGTT pattern in the pregnant Nigerian may be accounted for by a more efficient absorption of glucose.

Adolescent↗
PubMed1981

Complications of female circumcision in Nigerian Igbos.

An analysis is made of 43 children and 15 adult female patients who presented with post-circumcision complications at the University of Nigeria Teaching Hospital, Enugu, between January 1973 and December 1980; 57 patients had been circumcised within 21 days of birth and one patient in the seventh month of her first pregnancy. Age of presentation varied with the severity of the symptoms: 21 children and 11 adults presented with varying degrees of labial occlusion, while 9 children and 4 adults had implantation dermoids. Urinary retention was the problem in 12 children and one adult.

Adolescent↗
PubMed1981

Calcium metabolism in African primigravids.

Serum calcium inorganic phosphorus, protein and alkaline phosphatase as well as urine calcium were studied in fifty-five primigravid Nigerian women during pregnancy and postnatal period. Each patient was seen at the various stages of pregnancy and thus acted as her own control. Serum calcium levels fell with progressing pregnancy. Urine calcium showed a highly significant decrease throughout pregnancy and in the puerperium. Alkaline phosphatase showed a continuous rise with advancing gestation which was statistically highly significant, with a return towards normal values in the postnatal period. Serum inorganic phosphorus showed no significant alteration right through the pregnancy period. The normoproteinaemia seen in the group studied suggests that albumin did not make any contribution to the fall in the serum calcium levels seen during the study.

Adolescent↗
PubMed1980

Triplet pregnancy: a review of 27 cases.

Analysis of 27 consecutive triplet pregnancies seen at the University Teaching Hospital in Enugu, Nigeria, from 1972 to 1979 revealed an incidence of one in 1014 live births; three of these mothers had had a previous twin pregnancy. Overall fetal mortality was 30.9%, with babies of older women faring better than those of the younger. The fetal death rate was 1.8 times greater in the absence of antenatal supervision. Although the male infant was generally heavier at birth, sex did not influence survival and neither predominated. Surprisingly, vertex delivery, independent of birth order, was associated with the worst prognosis. All babies of sets having a combined birth weight of 2800 gm and under died; all those 5440 gm and above survived. Maturity, rather than birth weight, determined fetal survival, which was also unaffected by time interval between deliveries of a set. The first triplet did have the least birth hazard.

Adolescent↗
PubMed1980

Bladder calculus with pregnancy.

A case is reported of a 42-year-old pregnant woman with an asymptomatic bladder calculus. Diagnosis and management are discussed, and the literature is reviewed.

Adult↗