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V E Iaroslavskiĭ

Publications and source records attributed to V E Iaroslavskiĭ.

9 recordsLinked to original sources
PubMedDate not supplied

[The decreased susceptibility of Syrian hamsters to Opisthorchis felineus invasion after its repeated administration].

The investigations conducted on Syrian hamsters have revealed that multiple enteral infusions of cold inactivated (t = -10 degrees C) O. felineus metacercariae resulted in the formation of immunocompetent cell and fibroblast infiltrations around the branches of the portal vein. The infestation of animals by viable pathogens led to reduced accommodation of helminths and suppressed cell infiltration in the liver. It is assumed that the native population of the foci become tolerant to the disease with the penetration of noninvasive Opisthorchis larvae into their body and the development of latent forms of helminthiasis.

Animals↗
PubMedDate not supplied

[Pathomorphology of the reparative processes of the liver following praziquantel treatment of experimental opisthorchiasis].

The authors attempted to create a model of reparative processes in the liver in the residual period of experimental opisthorchiasis. The experiment was performed in 150 Opisthorchis invaded Syrian hamsters treated with praziquantel in a single dose of 400 mg/kg body weight on days 7-180 of postinfection. The studies of morphological, histochemical and morphometric alterations in the animal liver allowed one to distinguish the stages of additional sensitization, early and late rehabilitative changes and the stage of residual changes. An inverse relationship was found between the duration of last three stages with the invasion duration prior to treatment and with increased duration of the first stage of the disease in early therapy.

Animals↗